肾上腺素和阿托品对山羊催产素诱导发情的影响。

The effects of adrenaline and atropine on oxytocin-induced estrus in the goat.

作者信息

Cooke R G, Payne J H

机构信息

Department of Veterinary Preclinical Sciences University of Liverpool Veterinary Field Station Leahurst, Chester High Road, Neston South Wirral, Cheshire, L64 7TE, United Kingdom.

出版信息

Theriogenology. 1992 Apr;37(4):761-7. doi: 10.1016/0093-691x(92)90039-t.

DOI:10.1016/0093-691x(92)90039-t

PMID:16727077

Abstract

Oxytocin-induced luteolysis in goats was associated with significant increases in peripheral plasma concentrations of 13,14-dihydro-15-keto-prostaglandin (PG) F(2alpha) (PGFM). This effect was not inhibited by concomitant administration of adrenaline (1 mg), although increases of PGFM were both delayed and diminished. Administration of atropine, a muscarinic cholinergic antagonist, inhibited the effect of oxytocin in three out of five goats. In these animals, increases in PGFM were inhibited.

摘要

催产素诱导山羊黄体溶解与外周血浆中13,14-二氢-15-酮-前列腺素（PG）F（2α）（PGFM）浓度显著升高有关。尽管PGFM的升高有所延迟且幅度减小，但同时给予肾上腺素（1毫克）并不能抑制这种作用。给予毒蕈碱型胆碱能拮抗剂阿托品可抑制五分之三只山羊的催产素作用。在这些动物中，PGFM的升高受到抑制。