Nguemeving Jean Robert, Azebaze Anatole Guy Blaise, Kuete Victor, Eric Carly Nono Nono, Beng Véronique Penlap, Meyer Michèle, Blond Alain, Bodo Bernard, Nkengfack Augustin Ephrem
Department of Organic Chemistry, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon.
Phytochemistry. 2006 Jul;67(13):1341-6. doi: 10.1016/j.phytochem.2006.03.018. Epub 2006 Jun 5.
A phytochemical investigation of the constituents of the roots of Vismia laurentii has resulted in the isolation of two xanthone derivatives named laurentixanthone A (1) (6-hydroxy-3,3-dimethyl-11-(3-methylbut-2-enyl)pyrano[2,3-c]xanthen-7(3H)-one) and laurentixanthone B (2) (1-hydroxy-5,6,7,8-tetramethoxyxanthone), along with 11 known compounds: 1,7-dihydroxyxanthone, vismiaquinone, vismiaquinone B, bivismiaquinone, 3-geranyloxy-6-methyl-1,8-dihydroxyanthraquinone, O(1)-demethyl-3',4'-deoxypsorospermin-3',4'-diol, 6-deoxyisojacareubin, 1,8-dihydroxy-6-methoxy-3-methylanthraquinone, kaempferol, friedelin and stigmasterol. The structures of compounds were established by means of spectroscopic methods. Furthermore, the compounds were screened for antimicrobial activities in vitro.
对劳伦维斯米草（Vismia laurentii）根的成分进行植物化学研究，已分离出两种呫吨酮衍生物，分别命名为劳伦呫吨酮A（1）（6-羟基-3,3-二甲基-11-（3-甲基丁-2-烯基）吡喃并[2,3-c]呫吨-7（3H）-酮）和劳伦呫吨酮B（2）（1-羟基-5,6,7,8-四甲氧基呫吨酮），以及11种已知化合物：1,7-二羟基呫吨酮、维斯米醌、维斯米醌B、双维斯米醌、3-香叶氧基-6-甲基-1,8-二羟基蒽醌、O（1）-去甲基-3',4'-脱氧假苏木精-3',4'-二醇、6-脱氧异巴西苏木素、1,8-二羟基-6-甲氧基-3-甲基蒽醌、山柰酚、木栓酮和豆甾醇。通过光谱方法确定了化合物的结构。此外，还对这些化合物进行了体外抗菌活性筛选。
