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Is the measurement of monocytes HLA-DR expression useful in patients with sepsis?

作者信息

Fumeaux Thierry, Pugin Jérôme

出版信息

Intensive Care Med. 2006 Aug;32(8):1106-8. doi: 10.1007/s00134-006-0205-7. Epub 2006 Jun 2.

DOI:10.1007/s00134-006-0205-7
PMID:16741699
Abstract
摘要

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Is the measurement of monocytes HLA-DR expression useful in patients with sepsis?测量单核细胞 HLA - DR 表达对脓毒症患者有用吗？
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2
Altered leukocyte immunophenotypes in septic shock. Studies of HLA-DR, CD11b, CD14, and IL-2R expression.脓毒性休克中白细胞免疫表型的改变。HLA-DR、CD11b、CD14和IL-2R表达的研究。
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3
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5
Modulation of human leukocyte antigen-DR on monocytes and CD16 on granulocytes in patients with septic shock using hemoperfusion with polymyxin B-immobilized fiber.使用多粘菌素B固定化纤维血液灌流对感染性休克患者单核细胞上人类白细胞抗原-DR及粒细胞上CD16的调节作用。
Am J Surg. 2004 Aug;188(2):150-6. doi: 10.1016/j.amjsurg.2003.12.067.
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Ann Biol Clin (Paris). 2003 Jul-Aug;61(4):441-8.
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Massive increase in monocyte HLA-DR expression can be used to discriminate between septic shock and hemophagocytic lymphohistiocytosis-induced shock.单核细胞HLA-DR表达的大量增加可用于区分脓毒性休克和噬血细胞性淋巴组织细胞增生症所致休克。
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本文引用的文献

1
Down-modulation of granulocyte macrophage-colony stimulating factor receptor on monocytes during human septic shock.人类脓毒症休克期间单核细胞上粒细胞巨噬细胞集落刺激因子受体的下调
Crit Care Med. 2006 Apr;34(4):1193-201. doi: 10.1097/01.CCM.0000207339.11477.62.
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Reprogramming of circulatory cells in sepsis and SIRS.脓毒症和全身炎症反应综合征中循环细胞的重编程。
J Endotoxin Res. 2005;11(5):311-20. doi: 10.1179/096805105X58733.
3
Monitoring temporary immunodepression by flow cytometric measurement of monocytic HLA-DR expression: a multicenter standardized study.
脓毒症诱导免疫细胞凋亡的病理改变及治疗意义。
Cell Death Dis. 2019 Oct 14;10(10):782. doi: 10.1038/s41419-019-2015-1.
4
Smoking, Gender, and Overweight Are Important Influencing Factors on Monocytic HLA-DR before and after Major Cancer Surgery.吸烟、性别和超重是重大癌症手术后单核细胞 HLA-DR 前后的重要影响因素。
Biomed Res Int. 2017;2017:5216562. doi: 10.1155/2017/5216562. Epub 2017 Aug 8.
5
Diagnostic accuracy and clinical relevance of an inflammatory biomarker panel for sepsis in adult critically ill patients.成人重症患者中用于脓毒症的炎症生物标志物组合的诊断准确性及临床相关性
Diagn Microbiol Infect Dis. 2016 Feb;84(2):175-80. doi: 10.1016/j.diagmicrobio.2015.10.003. Epub 2015 Oct 9.
6
Granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF) for sepsis: a meta-analysis.粒细胞集落刺激因子（G-CSF）和粒细胞-巨噬细胞集落刺激因子（GM-CSF）治疗脓毒症：一项荟萃分析。
Crit Care. 2011;15(1):R58. doi: 10.1186/cc10031. Epub 2011 Feb 10.
7
Differential down-regulation of HLA-DR on monocyte subpopulations during systemic inflammation.全身性炎症期间单核细胞亚群 HLA-DR 的差异下调。
Crit Care. 2010;14(2):R61. doi: 10.1186/cc8959. Epub 2010 Apr 13.
8
Immunosuppressive CD14+HLA-DRlow/- monocytes in prostate cancer.前列腺癌中的免疫抑制性 CD14+HLA-DRlow/-单核细胞。
Prostate. 2010 Mar 1;70(4):443-55. doi: 10.1002/pros.21078.
9
The compensatory anti-inflammatory response syndrome (CARS) in critically ill patients.危重病患者的代偿性抗炎反应综合征（CARS）。
Clin Chest Med. 2008 Dec;29(4):617-25, viii. doi: 10.1016/j.ccm.2008.06.010.
10
Molecular and cellular aspects of sepsis-induced immunosuppression.脓毒症诱导免疫抑制的分子与细胞层面
J Mol Med (Berl). 2008 May;86(5):495-506. doi: 10.1007/s00109-007-0300-4. Epub 2008 Feb 8.
通过流式细胞术检测单核细胞 HLA-DR 表达监测暂时性免疫抑制：一项多中心标准化研究
Clin Chem. 2005 Dec;51(12):2341-7. doi: 10.1373/clinchem.2005.052639. Epub 2005 Oct 7.
4
Human leukocyte antigen expression in sepsis: what have we learned?脓毒症中人类白细胞抗原的表达：我们了解到了什么？
Crit Care Med. 2005 Jan;33(1):236-7. doi: 10.1097/01.ccm.0000150835.66819.ca.
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Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients.脓毒性休克患者全血中主要组织相容性复合体II类基因的信使核糖核酸表达
Crit Care Med. 2005 Jan;33(1):31-8; discussion 236-7. doi: 10.1097/01.ccm.0000150958.20209.a3.
6
Monocyte human leukocyte antigen-DR transcriptional downregulation by cortisol during septic shock.脓毒症休克期间皮质醇对人单核细胞人类白细胞抗原-DR的转录下调作用
Am J Respir Crit Care Med. 2004 May 15;169(10):1144-51. doi: 10.1164/rccm.200309-1329OC. Epub 2004 Mar 17.
7
Is monocyte HLA-DR expression predictive for clinical outcome in sepsis?
Intensive Care Med. 2003 Aug;29(8):1211-2. doi: 10.1007/s00134-003-1820-1.
8
Reversal of immunoparalysis by recombinant human granulocyte-macrophage colony-stimulating factor in patients with severe sepsis.重组人粒细胞巨噬细胞集落刺激因子对严重脓毒症患者免疫麻痹的逆转作用
Intensive Care Med. 2003 Apr;29(4):646-51. doi: 10.1007/s00134-003-1666-6. Epub 2003 Feb 21.
9
The immunopathogenesis of sepsis.脓毒症的免疫发病机制。
Nature. 2002;420(6917):885-91. doi: 10.1038/nature01326.
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"Septic Plasma": an immunosuppressive milieu.
Am J Respir Crit Care Med. 2002 Dec 1;166(11):1417-8. doi: 10.1164/rccm.2209003.