Jones Ellen, Thrall Donald, Dewhirst Mark W, Vujaskovic Zeljko
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.
Int J Hyperthermia. 2006 May;22(3):247-53. doi: 10.1080/02656730600765072.
This review summarizes recent results from two randomized trials testing the complete response rate and local control benefits for the addition of hyperthermia to external beam radiation.
In both series, there was a statistically significant benefit to adjuvant hyperthermia.
The establishment of a standardized nomenclature for clinical hyperthermia prescription will help to facilitate the broader usage of hyperthermia.
Carefully conducted phase III trials with rigorous quality assurance must employ prospective thermal dosimetry to validate the role of hyperthermia in multi-modality therapy.
本综述总结了两项随机试验的近期结果，这两项试验测试了在体外放射治疗中添加热疗的完全缓解率和局部控制益处。
在这两个系列中，辅助热疗都有统计学上的显著益处。
建立临床热疗处方的标准化命名法将有助于促进热疗的更广泛应用。
精心开展且有严格质量保证的III期试验必须采用前瞻性热剂量测定法来验证热疗在多模式治疗中的作用。
