Michie Katharine A, Löwe Jan
Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 2QH, UK.
Annu Rev Biochem. 2006;75:467-92. doi: 10.1146/annurev.biochem.75.103004.142452.
Bacterial cells contain a variety of structural filamentous proteins necessary for the spatial regulation of cell shape, cell division, and chromosome segregation, analogous to the eukaryotic cytoskeletal proteins. The molecular mechanisms by which these proteins function are beginning to be revealed, and these proteins show numerous three-dimensional structural features and biochemical properties similar to those of eukaryotic actin and tubulin, revealing their evolutionary relationship. Recent technological advances have illuminated links between cell division and chromosome segregation, suggesting a higher complexity and organization of the bacterial cell than was previously thought.
细菌细胞含有多种结构丝状蛋白，这些蛋白对于细胞形状、细胞分裂和染色体分离的空间调控是必需的，类似于真核细胞的细胞骨架蛋白。这些蛋白发挥功能的分子机制正开始被揭示，并且这些蛋白展现出许多与真核肌动蛋白和微管蛋白相似的三维结构特征和生化特性，揭示了它们的进化关系。最近的技术进步阐明了细胞分裂与染色体分离之间的联系，这表明细菌细胞比之前认为的具有更高的复杂性和组织性。
