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呼吸机相关性肺炎经验性抗菌治疗的比较评价

[Comparative evaluation of empirical antibacterial therapy for ventilator-associated pneumonia].

作者信息

Mkhoian G G, Akopian G P

出版信息

Anesteziol Reanimatol. 2006 Mar-Apr(2):57-61.

Abstract

The problem of nosocomial pneumonias remains most urgent for intensive care units so far. Particular emphasis is placed on clinical and diagnostic monitoring and therapy for ventilation-induced nosocomial pneumonias (VINP) in intensive care patients on ventilation. This is accounted for by not only the high incidence of this pathology, but also by its severity and mortality rates. In the pattern of nosocomial complications, pneumonia ranks second-third in its prevalence, which accounts for about 10-15%, and first in mortality rates (30%); it afflicts 50% of the elderly patients on ventilation. Antibacterial therapy plays a great role in ventilation therapy. The study deals with the comparative characteristics of empirical antibacterial therapy for VINP.

摘要

迄今为止,医院获得性肺炎问题对于重症监护病房来说仍然最为紧迫。特别强调对接受通气治疗的重症监护患者的机械通气相关性医院获得性肺炎(VINP)进行临床和诊断监测及治疗。这不仅是由于这种病症的高发病率,还因其严重性和死亡率。在医院获得性并发症模式中,肺炎在患病率方面排名第二至第三,约占10 - 15%,而在死亡率方面排名第一(30%);它折磨着50%接受通气治疗的老年患者。抗菌治疗在通气治疗中起着重要作用。该研究探讨了VINP经验性抗菌治疗的比较特征。

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