Rinberg Dmitry, Gelperin Alan
Monell Chemical Senses Center, 3500 Market St., Philadelphia, PA 19104, USA.
Semin Cell Dev Biol. 2006 Aug;17(4):454-61. doi: 10.1016/j.semcdb.2006.04.009. Epub 2006 May 5.
More than 50 years have passed since the first recording of neuronal responses to an odor stimulus from the primary olfactory brain area, the main olfactory bulb. During this time very little progress has been achieved in understanding neuronal dynamics in the olfactory bulb in awake behaving animals, which is very different from that in anesthetized preparations. In this paper we formulate a new framework containing the main reasons for studying olfactory neuronal dynamics in awake animals and review advances in the field within this new framework.
自从首次记录到来自主要嗅觉脑区——主嗅球对气味刺激的神经元反应以来，已经过去了50多年。在此期间，在理解清醒行为动物嗅球中的神经元动态方面进展甚微，这与麻醉状态下的动物截然不同。在本文中，我们构建了一个新的框架，其中包含研究清醒动物嗅觉神经元动态的主要原因，并在这个新框架内回顾了该领域的进展。
