Suzuki Jun, Goto Hiroshi, Minoda Hiroshi, Iwasaki Takuya, Sakai J, Usui Masahiko
Department of Ophthalmology, Tokyo Medical University Hospital, Tokyo, Japan.
Ocul Immunol Inflamm. 2006 Jun;14(3):165-70. doi: 10.1080/09273940600672198.
To analyze the retinal findings in patients with ARN, optical coherence tomography (OCT) was performed.
Seven patients (7 eyes) with ARN were studied using OCT.
OCT images depicted highly reflective areas in the inner layers of the retina in all seven cases, corresponding with the yellowish-white lesions of the retina in the acute phase. Disorganization of the retinal structure was also observed in these retinal lesions, especially in cases with severe inflammation. Subretinal changes including retinal exudate and/or fluid were observed in only one case. After regression of the yellowish-white lesions in the retina, a significant reduction in retinal thickness was observed on OCT.
OCT permits the detection of full-thickness retinal necrosis in the acute phase and complete absence of retinal structure in the resolution phase, corresponding with the yellowish-white lesions seen in patients with ARN.
为分析急性视网膜坏死(ARN)患者的视网膜表现,进行了光学相干断层扫描(OCT)检查。
对7例(7只眼)ARN患者进行了OCT研究。
OCT图像显示,所有7例患者视网膜内层均有高反射区,与急性期视网膜黄白色病变相对应。在这些视网膜病变中还观察到视网膜结构紊乱,尤其是在炎症严重的病例中。仅1例观察到包括视网膜渗出物和/或液体积聚在内的视网膜下改变。视网膜黄白色病变消退后,OCT显示视网膜厚度显著降低。
OCT能够检测急性期全层视网膜坏死以及消退期视网膜结构完全消失,这与ARN患者所见的黄白色病变相符。