Marschall S, Rothschild M A, Bohnert M
Institute of Legal Medicine, Albert Ludwig University, Albertstrasse 9, 79104 Freiburg, Germany.
Int J Legal Med. 2006 Nov;120(6):355-9. doi: 10.1007/s00414-006-0105-y. Epub 2006 May 31.
Immunohistochemical investigation of the respiratory tract and lungs of 63 fire victims revealed a statistically significant enhanced expression of heat-shock protein 70 (Hsp70) in the epiglottis, the trachea, and the main and the peripheral bronchi compared with a control group. In the fire victims, a strong expression of Hsp70 was discernible not only particularly in the vessels but also in seromucous secretory cells, ciliated epithelial cells, smooth muscle cells, and alveolar cells. The results suggest a vital or supravital reaction due to the inhalation of hot fire fumes.
对63名火灾受害者的呼吸道和肺部进行免疫组织化学研究发现，与对照组相比，会厌、气管、主支气管和外周支气管中热休克蛋白70（Hsp70）的表达在统计学上显著增强。在火灾受害者中，不仅在血管中，而且在浆液黏液分泌细胞、纤毛上皮细胞、平滑肌细胞和肺泡细胞中都能明显看到Hsp70的强烈表达。结果表明，吸入热火烟雾会引发重要或超重要反应。
