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一项比较1072纳米光与安慰剂治疗唇疱疹效果的随机双盲研究。

A randomised double-blind study comparing the effect of 1072-nm light against placebo for the treatment of herpes labialis.

作者信息

Hargate G

机构信息

Newlands Medical Centre, Borough Road, Middlesbrough, UK.

出版信息

Clin Exp Dermatol. 2006 Sep;31(5):638-41. doi: 10.1111/j.1365-2230.2006.02191.x. Epub 2006 Jun 15.

Abstract

BACKGROUND

Previous research demonstrated that 1072-nm narrowband laser light is effective in the treatment of cold sores.

AIM

To evaluate the efficacy of an over-the-counter cold-sore treatment device (Virulite CS) incorporating 1072-nm light-emitting diodes.

METHODS

A randomised, prospective, double-blind, self-reported study was performed to compare the efficacy of at least six 3-min treatments of 1072-nm narrowband light against placebo, in the treatment of herpes labialis.

RESULTS

The 1072-nm light-emitting diode device reduced cold-sore healing time to 6.3 days compared with 9.4 days for placebo (P=0.048). The time the cold sore took to form a crust was also reduced from 2.00 days for those treated with 1072-nm light, compared with 2.88 days for placebo (P=0.059)

CONCLUSIONS

The significant difference between the mean healing times in the two groups demonstrates that the Virulite CS device is an effective means of treating herpes labialis.

摘要

背景

先前的研究表明,1072纳米窄带激光对唇疱疹的治疗有效。

目的

评估一种采用1072纳米发光二极管的非处方唇疱疹治疗设备(Virulite CS)的疗效。

方法

开展一项随机、前瞻性、双盲、自我报告的研究,比较1072纳米窄带光至少6次3分钟治疗与安慰剂治疗唇疱疹的疗效。

结果

与安慰剂组的9.4天相比,1072纳米发光二极管设备将唇疱疹愈合时间缩短至6.3天(P = 0.048)。与安慰剂组的2.88天相比,接受1072纳米光治疗的患者唇疱疹结疤时间也从2.00天缩短(P = 0.059)。

结论

两组平均愈合时间的显著差异表明,Virulite CS设备是治疗唇疱疹的有效手段。

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