Kim Myo-Kyoung, Choi Sun-Young, Byun Hee-Jin, Huh Chang-Hun, Park Kyoung-Chan, Patel Rajul A, Shinn Annie H, Youn Sang-Woong
Pharmacy Practice, University of the Pacific, Thomas J. Long School of Pharmacy, 751 Brookside Road, Stockton, CA 95211, USA.
Arch Dermatol Res. 2006 Aug;298(3):113-9. doi: 10.1007/s00403-006-0666-0. Epub 2006 Jun 20.
Differences of skin type and pH between subjects with and without acne have not been investigated. In addition, the relationship between sebum secretion and pH in these populations has not been determined. This study assessed the differences in objective and subjective skin types between these two groups. Secondly, this study evaluated the difference in pH on five facial areas (forehead, nose, chin, right and left cheeks) between the two populations. Lastly, the relationship between pH and sebum secretion was analyzed in each population. Sebum casual levels (CL) of the five facial areas in 36 Koreans with acne and 47 Koreans without acne were measured by using a Sebumeter SM 815 and subjects were classified into objective skin types by CL. Subjects reported the type of skin they believed they had, which determined the subjective skin type. The pH levels of the five facial areas were measured by the Skin-pH-Meter PH 905. Data were assessed with adequate statistical tests depending on data type and distribution. Among the five areas, the nose of the subjects with acne showed a significantly higher CL, compared to the subjects without acne. This difference in CL on the nose resulted in the difference in CL on the T-zone and mean facial sebum excretions (MFSE). Although CL differed, objective skin types did not differ between the two groups (P > 0.05), but the subjective skin types differed significantly (P = 0.001). In addition, the objective skin types were significantly different than the subjective skin types in subjects with acne (P = 0.001), whereas the two skin types did not differ in subjects without acne. Subjects with acne actually overestimated their skin types and stated their skin types were "oilier" than they were. In respect to pH, none of the five areas differed significantly between the two groups. Among the five sites in subjects with acne, CL showed a significant negative correlation with pH on the left (r (2 )=0.12) and right (r ( 2 )=0.15) cheeks, which resulted in a significant negative correlation on the U-zone (r ( 2 )=0.14). In contrast, in subjects without acne, there was a significant negative correlation between CL and pH on the forehead (r ( 2 )=0.10) and chin (r ( 2 )=0.16), which led to a significant negative correlation on the T-zone (r ( 2 )=0.14).
痤疮患者与非痤疮患者之间的皮肤类型和pH值差异尚未得到研究。此外，这些人群中皮脂分泌与pH值之间的关系也尚未确定。本研究评估了这两组人群在客观和主观皮肤类型上的差异。其次，本研究评估了这两个人群在五个面部区域（额头、鼻子、下巴、左右脸颊）的pH值差异。最后，分析了每个人群中pH值与皮脂分泌之间的关系。使用皮脂测量仪SM 815测量了36名患有痤疮的韩国人和47名未患痤疮的韩国人五个面部区域的皮脂随意水平（CL），并根据CL将受试者分为客观皮肤类型。受试者报告了他们认为自己拥有的皮肤类型，从而确定主观皮肤类型。使用皮肤pH计PH 905测量五个面部区域的pH值。根据数据类型和分布，用适当的统计检验对数据进行评估。在五个区域中，与未患痤疮的受试者相比，患有痤疮的受试者的鼻子显示出显著更高的CL。鼻子上CL的这种差异导致了T区CL和平均面部皮脂排泄量（MFSE）的差异。尽管CL有所不同，但两组之间的客观皮肤类型没有差异（P>0.05），但主观皮肤类型有显著差异（P=0.001）。此外，痤疮患者的客观皮肤类型与主观皮肤类型有显著差异（P=0.001），而在未患痤疮的受试者中，两种皮肤类型没有差异。患有痤疮的受试者实际上高估了他们的皮肤类型，并表示他们的皮肤类型比实际“更油”。关于pH值，两组之间五个区域中的任何一个都没有显著差异。在患有痤疮的受试者的五个部位中，CL与左脸颊（r（2）=0.12）和右脸颊（r（2）=0.15）的pH值呈显著负相关，这导致U区呈显著负相关（r（2）=0.14）。相比之下，在未患痤疮的受试者中，CL与额头（r（2）=0.10）和下巴（r（2）=0.16）的pH值呈显著负相关，这导致T区呈显著负相关（r（2）=0.14）。
