van Gemert-Horsthuis Karin, Florie Jasper, Hommes Daniel W, Lavini Cristina, Reitsma Johannes B, van Deventer Sander J, Stoker Jaap
Department of Radiology, Academic Medical Center, Amsterdam, The Netherlands.
J Magn Reson Imaging. 2006 Aug;24(2):340-8. doi: 10.1002/jmri.20650.
To determine whether abdominal 3.0T MRI can be used for evaluation of Crohn's disease (CD) compared with ileocolonoscopy (CS), and to determine patient preference for MRI as opposed to CS.
Twenty patients scheduled for CS underwent MRI. At CS, disease severity was graded and the Crohn's Disease Endoscopic Index of Severity (CDEIS) was determined. Radiological grading (by two observers) was compared with endoscopic grading and CDEIS. Patient experience and preference were determined.
In respectively 10 (observer 1) and 13 patients (observer 2) exact agreement between radiological and endoscopic grading was found. In respectively 10 and 7 patients radiological and endoscopic grading differed one level. No statistically significant correlation was found between radiological grading and CDEIS. Between bowel wall thickness and CDEIS weak to moderate correlations were found, and between bowel wall enhancement and CDEIS weak correlations were found. All patients preferred MRI over CS.
It is feasible to perform abdominal 3.0T MRI using orally administered contrast medium for evaluation of CD, and this method can be considered a patient-friendly alternative to CS.
确定腹部3.0T磁共振成像（MRI）与回结肠镜检查（CS）相比是否可用于评估克罗恩病（CD），并确定患者对MRI而非CS的偏好。
20例计划进行CS的患者接受了MRI检查。在CS检查时，对疾病严重程度进行分级，并确定克罗恩病内镜严重程度指数（CDEIS）。将放射学分级（由两名观察者进行）与内镜分级及CDEIS进行比较。确定患者的体验和偏好。
分别在10例患者（观察者1）和13例患者（观察者2）中发现放射学分级与内镜分级完全一致。分别在10例和7例患者中，放射学分级与内镜分级相差一级。放射学分级与CDEIS之间未发现统计学上的显著相关性。在肠壁厚度与CDEIS之间发现了弱至中度的相关性，在肠壁强化与CDEIS之间发现了弱相关性。所有患者都更倾向于选择MRI而非CS。
口服对比剂进行腹部3.0T MRI评估CD是可行的，该方法可被视为一种对患者友好的替代CS的检查方法。
