Chedraui Peter, Hidalgo Luis, Chavez Diana, Morocho Nancy, Alvarado Mariela, Huc Angelica
Institute of Biomedicine, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, PO Box 09-01-4671, Guayaquil, Ecuador.
Maturitas. 2007 Jan 20;56(1):45-53. doi: 10.1016/j.maturitas.2006.05.008. Epub 2006 Jun 23.
Quality of life decreases after the menopause as it has been assessed by several designed tools. Despite this, few studies have reported correlations between quality of life and the metabolic syndrome and its determinants.
Evaluate quality of life and determine factors related to its impairment among postmenopausal Ecuadorian women.
Postmenopausal women that participated in a metabolic syndrome screening and educational program at the Institute of Biomedicine of the Universidad Católica of Guayaquil, Ecuador were interviewed using the Menopause-Specific Quality of Life Questionnaire (MENQOL). Mean domain scores as well as factors associated to higher scores within each of the domains of the questionnaire (vasomotor, psycho-social, physical and sexual) were determined.
Three hundred twenty-five postmenopausal women (n=325) were surveyed. Mean age of participants was 55.9+/-8.1 years (median: 54 years). Women presented metabolic syndrome, hypertension, hyperglycemia, hypertriglyceridemia and abdominal obesity in 41.5%, 38.8%, 16.6%, 56.9% and 54.2% respectively. Mean scores obtained for each domain were: vasomotor: 3.5+/-2.5 (median 3); psycho-social: 3.7+/-1.5 (median 3.6); physical: 3.8+/-1.2 (median 3.8); sexual: 4.9+/-2.3 (median 5.3). More than 50% of women had scores above the median for each domain of the questionnaire. Logistic regression determined that vasomotor score decreased with age. Abdominal obesity increased the risk of having vasomotor, psycho-social and physical scores above the median. Hypertension and hyperglycemia increased the risk for higher scores within the psycho-social and sexual domain respectively.
In this postmenopausal Ecuadorian population, impairment of quality of life was found to be associated to age and related conditions such as abdominal obesity, hypertension and hyperglycemia.
通过多种设计工具评估发现,绝经后生活质量会下降。尽管如此,很少有研究报道生活质量与代谢综合征及其决定因素之间的相关性。
评估厄瓜多尔绝经后女性的生活质量,并确定与其受损相关的因素。
使用绝经特异性生活质量问卷(MENQOL)对参与厄瓜多尔瓜亚基尔天主教大学生物医学研究所代谢综合征筛查和教育项目的绝经后女性进行访谈。确定问卷各领域(血管舒缩、心理社会、身体和性方面)的平均领域得分以及与较高得分相关的因素。
共调查了325名绝经后女性(n = 325)。参与者的平均年龄为55.9±8.1岁(中位数:54岁)。女性代谢综合征、高血压、高血糖、高甘油三酯血症和腹型肥胖的发生率分别为41.5%、38.8%、16.6%、56.9%和54.2%。各领域的平均得分如下:血管舒缩方面:3.5±2.5(中位数3);心理社会方面:3.7±1.5(中位数3.6);身体方面:3.8±1.2(中位数3.8);性方面:4.9±2.3(中位数5.3)。超过50%的女性在问卷各领域的得分高于中位数。逻辑回归分析确定血管舒缩得分随年龄降低。腹型肥胖增加了血管舒缩、心理社会和身体得分高于中位数的风险。高血压和高血糖分别增加了心理社会和性领域得分较高的风险。
在这群厄瓜多尔绝经后人群中,发现生活质量受损与年龄以及腹型肥胖、高血压和高血糖等相关状况有关。