指甲组织真菌学聚焦

Spotlight on nail histomycology.

作者信息

Piérard Gérald E, Quatresooz Pascale, Arrese Jorge E

机构信息

Department of Dermatopathology, University Hospital of Liège, CHU Sart Tilman, B-4000 Liège, Belgium.

出版信息

Dermatol Clin. 2006 Jul;24(3):371-4. doi: 10.1016/j.det.2006.03.013.

DOI:10.1016/j.det.2006.03.013

PMID:16798435

Abstract

The misdiagnosis of onychomycosis delays the proper treatment of the nail condition. Nail histomycology refers to the microscopic examination of histologic sections prepared from nail clippings for the purpose of detecting the presence of fungi. This laboratory method is the most sensitive procedure for the diagnosis of onychomycosis. It allows for the visualization of the precise location of the invasive fungus inside the nail apparatus. The method also distinguishes various shapes of the fungal cells, in particular filamentous fungi, yeasts, conidia, and sporodochia. The correct diagnosis provided by histomycology combined with culture not only allows for more efficient expenditure of funds and services but also is important for the timely alleviation of the disorder.

摘要

甲癣的误诊会延误对指甲病症的正确治疗。指甲组织真菌学是指对从指甲剪屑制备的组织切片进行显微镜检查，以检测真菌的存在。这种实验室方法是诊断甲癣最敏感的程序。它能够观察到侵袭性真菌在指甲结构内的确切位置。该方法还能区分各种真菌细胞的形态，特别是丝状真菌、酵母、分生孢子和分生孢子座。组织真菌学与培养相结合提供的正确诊断不仅能更有效地使用资金和服务，而且对于及时缓解病情也很重要。