Yu Song-Hyeon, Lim Sang-Hyun, Hong You-Sun, Yoo Kyung-Jong, Chang Byung-Chul, Kang Meyun-Shick
Department of Thoracic and Cardiovascular Surgery, Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seodaemun-gu, Seoul 120-752, Korea.
Yonsei Med J. 2006 Jun 30;47(3):367-71. doi: 10.3349/ymj.2006.47.3.367.
Although cardiac myxoma is rare, it is the most common primary cardiac tumor. Seventy-four cases of cardiac myxoma that were surgically treated in our center between August 1980 and February 2005 were retrospectively reviewed. The mean patient age was 50.4 +/- 15.0 (range 7-80) years, and 53 patients (71.6%) were female. The most common preoperative symptom, occurring in 44 patients, was dyspnea. The interval from onset of symptoms to surgery was 9 months. Seventy cases were located in the left atrium, 3 in the right atrium and 1 in the right ventricle. The myxoma in the right ventricle could not be resected completely, due to severe infiltration. Cardiopulmonary bypass and aortic cross clamp times were 100.4 +/- 37.1 and 64.8 +/- 29.8 minutes, respectively. There were no hospital deaths, and 7 patients suffered from postoperative complications including atrial fibrillation in 2 cases. During the follow up period (mean 105.7 +/- 73.6 months), there was no tumor recurrence and 6 late deaths that were not related to the underlying tumor. There was no evidence of tumor growth in the cases with incomplete resection during the 14-month follow-up. In conclusion, in this study there was no recurrence of tumors after complete resection and surgical resection is considered to be the curative method of treatment for cardiac myxoma.
尽管心脏黏液瘤罕见,但它是最常见的原发性心脏肿瘤。对1980年8月至2005年2月间在我们中心接受手术治疗的74例心脏黏液瘤病例进行了回顾性分析。患者平均年龄为50.4±15.0岁(范围7 - 80岁),53例患者(71.6%)为女性。最常见的术前症状是呼吸困难,有44例患者出现该症状。从症状出现到手术的间隔时间为9个月。70例位于左心房,3例位于右心房,1例位于右心室。由于严重浸润,右心室的黏液瘤无法完全切除。体外循环和主动脉阻断时间分别为100.4±37.1分钟和64.8±29.8分钟。无住院死亡病例,7例患者出现术后并发症,其中2例发生心房颤动。在随访期(平均105.7±73.6个月),无肿瘤复发,6例晚期死亡与基础肿瘤无关。在14个月的随访中,未完全切除的病例无肿瘤生长迹象。总之,在本研究中,完全切除后无肿瘤复发,手术切除被认为是心脏黏液瘤的治愈性治疗方法。