Giordano Thomas P, Morgan Robert O, Kramer Jennifer R, Hartman Christine, Richardson Peter, White Clinton A, Suarez-Almazor Maria E, El-Serag Hashem B
Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
J Gen Intern Med. 2006 Jun;21(6):613-7. doi: 10.1111/j.1525-1497.2006.00452.x.
Disparities in survival for black patients with HIV in the United States have been reported. The VA is an equal access health care system.
To determine whether such disparities are present in the VA health care system.
Retrospective cohort study using national VA administrative databases.
Two thousand three hundred and four white and 3,641 black HIV-infected patients first hospitalized for HIV between October 1, 1996 and September 30, 2000.
Thirty-day mortality after first hospitalization with HIV, and subsequent long-term survival. Follow-up ended at death or September 30, 2002. Data were adjusted for age, sex, HIV disease severity, non-HIV-related comorbidities, primary discharge diagnosis, hepatitis C status, and facility effects.
The mean follow-up was 3.2 years. Overall survival was similar for black patients compared with white patients (adjusted hazard ratio 1.09, P=.09). Hospital mortality was 7.0% for black and 6.4% for white patients (P=.35). Adjusted hospital mortality for black patients was similar to that of white patients (odds ratio 1.20, P=.10). Long-term survival after hospitalization did not significantly differ by race (adjusted hazard ratio 1.07, P=.21, for black patients compared with white patients).
Survival during and after first hospitalization with HIV in the VA did not significantly differ for white and black patients, possibly indicating similar effectiveness of care for HIV. Further research is needed to understand the reasons for the lack of disparities for VA patients with HIV and whether the VA's results could be replicated.
据报道,美国感染艾滋病毒的黑人患者在生存方面存在差异。退伍军人事务部(VA)是一个提供平等医疗服务的系统。
确定退伍军人事务部医疗系统中是否存在此类差异。
使用退伍军人事务部全国行政数据库进行回顾性队列研究。
1996年10月1日至2000年9月30日期间首次因艾滋病毒住院的2304名白人艾滋病毒感染患者和3641名黑人艾滋病毒感染患者。
首次艾滋病毒住院后的30天死亡率及随后的长期生存率。随访至死亡或2002年9月30日结束。数据针对年龄、性别、艾滋病毒疾病严重程度、非艾滋病毒相关合并症、主要出院诊断、丙型肝炎状况及医疗机构影响进行了调整。
平均随访时间为3.2年。黑人患者与白人患者的总体生存率相似(调整后的风险比为1.09,P = 0.09)。黑人患者的医院死亡率为7.0%,白人患者为6.4%(P = 0.35)。黑人患者调整后的医院死亡率与白人患者相似(优势比为1.20,P = 0.10)。住院后的长期生存率在种族间无显著差异(黑人患者与白人患者相比,调整后的风险比为1.07,P = 0.21)。
退伍军人事务部中,白人患者和黑人患者首次艾滋病毒住院期间及之后的生存率无显著差异,这可能表明对艾滋病毒的治疗效果相似。需要进一步研究以了解退伍军人事务部艾滋病毒患者不存在差异的原因,以及退伍军人事务部的结果是否能够推广。