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[墨西哥韦拉克鲁斯州登革热和钩端螺旋体抗体的流行情况]

[Prevalence of dengue and leptospira antibodies in the state of Veracruz, Mexico].

作者信息

Navarrete-Espinosa Joel, Acevedo-Vales Juan Antonio, Huerta-Hernández Emilia, Torres-Barranca Jorge, Gavaldón-Rosas Dolores Guadalupe

机构信息

Coordinación de Programas Integrados de Salud, Unidad de Salud Pública, Instituto Mexicano del Seguro Social, DF México.

出版信息

Salud Publica Mex. 2006 May-Jun;48(3):220-8. doi: 10.1590/s0036-36342006000300006.

Abstract

OBJECTIVE

To discover the prevalence of antibodies against denguevirus and leptospira.

MATERIAL AND METHODS

A cross-sectional study was carried out in 500 inhabitants of Veracruz, Mexico through household sampling, administration of a questionnaire and collection of blood samples.The presence of IgG antibodies was determined and factors associated with seroprevalence were evaluated using a logistic regression model.

RESULTS

Total denguevirus seroprevalence was 79.6% (IC 95% 76-81). The main factors associated with infection were age and residence in neighborhoods with higher vectorial indices (RMP = 2.94, IC 95% 1.46-6.1). Overall seroprevalence against leptospira was 4% (IC 95% 2-6). Prevalence was higher in the 25 to 44 years age group (35%, IC 95% 15-59). Seroprevalence in individuals who referred to living with dogs, pigs, cows and rats was 25% (IC 95% 0.63-80). Eighty-five percent of individuals who were leptospira positive were also dengue positive.

CONCLUSIONS

The prevalence of denguevirus antibodies suggests the risk of serious dengue hemorrhagic outbreaks. Although leptospirosis prevalence was low, the coexistence of both agents was confirmed.

摘要

目的

了解登革病毒和钩端螺旋体抗体的流行情况。

材料与方法

通过家庭抽样、问卷调查和血样采集,对墨西哥韦拉克鲁斯州的500名居民进行了一项横断面研究。测定了IgG抗体的存在情况,并使用逻辑回归模型评估了与血清阳性率相关的因素。

结果

登革病毒总血清阳性率为79.6%(95%置信区间76 - 81)。与感染相关的主要因素是年龄和居住在病媒指数较高的社区(比值比 = 2.94,95%置信区间1.46 - 6.1)。钩端螺旋体的总体血清阳性率为4%(95%置信区间2 - 6)。在25至44岁年龄组中患病率较高(35%,95%置信区间15 - 59)。报告与狗、猪、牛和鼠生活在一起的个体的血清阳性率为25%(95%置信区间0.63 - 80)。85%的钩端螺旋体阳性个体同时也是登革热阳性。

结论

登革病毒抗体的流行表明存在严重登革出血热暴发的风险。尽管钩端螺旋体病的患病率较低,但证实了两种病原体共存。

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