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在比尔森(捷克)住院儿童中诊断星状病毒感染的首次经验。

First experience with diagnosing astroviral infections in children hospitalized in Pilsen (Czechia).

作者信息

Pazdiora P, Jelínková H, Svecová M, Táborská J

机构信息

Institute of Epidemiology, Medical Faculty, Charles University, 305 99 Pilsen, Czechia.

出版信息

Folia Microbiol (Praha). 2006;51(2):129-32. doi: 10.1007/BF02932167.

DOI:10.1007/BF02932167
PMID:16821722
Abstract

Between the years 2000-2002 astroviral infection was confirmed in 0.8 % of 2606 children admitted for a diarrheal disease to the University Hospital in Pilsen (Czechia). Astrovirus infections most frequently occurred in the age group between 49-60 months, and 77.3 % of the infections occurred in winter. When the incidence was calculated for these most susceptible age groups, the positive rates were 2.4 % (between 49-60 months) and 1.2 % (between 7-12 months) respectively. On average the hospitalization lasted for 5 d, the diarrhea 3.7 d, vomiting 1.1 d, and 40.9 % of infected children had a raised temperature. In 7 out of 872 stool samples (0.8 %), astrovirus antigen has appeared in the course of the monitored period, i.e. nosocomial astrovirus infection was recorded. In view of the rarity of detecting astroviral infections it is probably not effective to include the diagnosis of these infections in the routine panel when examining the children admitted for gastrointestinal infections. The diagnosis of these infections should, however, be performed within the framework of epidemic incidence and in nosocomial infections.

摘要

2000年至2002年期间,在比尔森大学医院(捷克)因腹泻病入院的2606名儿童中,0.8%被确诊为星状病毒感染。星状病毒感染最常发生在49至60个月龄的儿童中,77.3%的感染发生在冬季。当计算这些最易感年龄组的发病率时,阳性率分别为2.4%(49至60个月)和1.2%(7至12个月)。平均住院时间为5天,腹泻3.7天,呕吐1.1天,40.9%的感染儿童体温升高。在872份粪便样本中的7份(0.8%)中,在监测期间检测到星状病毒抗原,即记录到医院内星状病毒感染。鉴于检测星状病毒感染的情况罕见,在检查因胃肠道感染入院的儿童时,将这些感染的诊断纳入常规检测项目可能无效。然而,这些感染的诊断应在流行发病范围内以及医院感染中进行。

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One-year survey of astrovirus infection in children with gastroenteritis in a large hospital in Hungary: occurrence and genetic analysis of astroviruses.匈牙利一家大型医院对肠胃炎患儿星状病毒感染的一年期调查:星状病毒的发生率及基因分析
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A simple and rapid single-step multiplex RT-PCR to detect Norovirus, Astrovirus and Adenovirus in clinical stool samples.
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Childhood astrovirus-associated diarrhea in the ambulatory setting in a Public Hospital in Cordoba city, Argentina.阿根廷科尔多瓦市一家公立医院门诊环境中与儿童星状病毒相关的腹泻
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