Boskey Adele L
Hospital for Special Surgery, 535 E. 70th Street, New York, NY 10021, USA.
Curr Osteoporos Rep. 2006 Jun;4(2):71-5. doi: 10.1007/s11914-006-0005-6.
The resistance of bone to fracture is determined by its geometric and material properties. The geometry and density can be determined by radiographic methods, but material properties such as collagen structure, mineral composition, and crystal structure currently require analysis by invasive techniques. Backscatter electron imaging provides quantitative information on the distribution of the mineral within tissue sections, and infrared and other vibrational spectroscopic methods can supplement these data, providing site-specific information on mineral content as well as information on collagen maturity and distributions of crystal size and composition. This information contributes to the knowledge of "bone quality."
骨骼对骨折的抵抗力由其几何和材料特性决定。几何形状和密度可通过放射成像方法确定，但诸如胶原蛋白结构、矿物质组成和晶体结构等材料特性目前需要通过侵入性技术进行分析。背散射电子成像可提供组织切片内矿物质分布的定量信息，红外和其他振动光谱方法可补充这些数据，提供有关矿物质含量的特定部位信息以及有关胶原蛋白成熟度、晶体大小和组成分布的信息。这些信息有助于了解“骨质量”。
