Kayali U, Mindekem R, Hutton G, Ndoutamia A G, Zinsstag J
International Committee of the Red Cross, Geneva, Switzerland.
Trop Med Int Health. 2006 Jul;11(7):1058-65. doi: 10.1111/j.1365-3156.2006.01663.x.
In the discussion about policies and strategies for rabies prevention in developing countries, intervention costs arise as a major issue. In a pilot mass vaccination campaign against rabies in N'Djaména, Chad, 3000 dogs were vaccinated. We assessed vaccination coverage and cost, showing the cost per dog vaccinated for the public sector and for society. An extrapolation to city level calculated the approximate cost of vaccinating all 23 600 dogs in N'Djaména. In the pilot mass campaign with 3000 dogs the average cost per dog was 1.69 euro. to the public and the full societal cost was 2.45 euro. If all 23 600 dogs in N'Djaména were vaccinated, the average cost would fall to 1.16 euro to the public and 1.93 euro to society. Private sector costs account for 31% of the cost to vaccinate 3000 dogs, and 40% of the cost to vaccinate 23 600 dogs. Mass dog vaccination could be a comparatively cheap and ethical way to both control the disease in animals and prevent human cases and exposure, especially in developing countries. The cost-effectiveness of dog vaccination compared with treating victims of dog bites for prevention of human rabies should be further assessed and documented.
在关于发展中国家狂犬病预防政策和策略的讨论中,干预成本成为一个主要问题。在乍得恩贾梅纳开展的一次大规模狂犬病疫苗接种试点活动中,为3000只狗接种了疫苗。我们评估了疫苗接种覆盖率和成本,展示了公共部门和社会为每只狗接种疫苗的成本。通过外推至城市层面,计算出为恩贾梅纳所有23600只狗接种疫苗的大致成本。在有3000只狗参与的试点大规模活动中,每只狗的平均成本对公共部门而言为1.69欧元,对整个社会而言为2.45欧元。如果为恩贾梅纳所有23600只狗接种疫苗,平均成本将降至对公共部门而言为1.16欧元,对社会而言为1.93欧元。私营部门成本占为3000只狗接种疫苗成本的31%,占为23600只狗接种疫苗成本的40%。大规模犬类疫苗接种可能是一种相对廉价且符合伦理的方法,既能控制动物疾病,又能预防人类病例和暴露,尤其是在发展中国家。与治疗犬咬伤受害者以预防人类狂犬病相比,犬类疫苗接种的成本效益应进一步评估并记录在案。