32岁人群中的口干症与药物
Xerostomia and medications among 32-year-olds.
作者信息
Murray Thomson William, Poulton Richie, Mark Broadbent Jonathan, Al-Kubaisy Shaima
机构信息
Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.
出版信息
Acta Odontol Scand. 2006 Aug;64(4):249-54. doi: 10.1080/00016350600633243.
OBJECTIVE
To describe the prevalence and associations of xerostomia among adults in their early thirties, with particular attention to medication exposure as a putative risk factor.
MATERIAL AND METHODS
The prevalence and associations of xerostomia were investigated among 32-year-old participants in a long-standing prospective cohort study. Some 950 individuals were assessed at ages 26 and 32 years, with medications being recorded on both occasions.
RESULTS
The prevalence of xerostomia was 10.0% (with no apparent gender difference), and was significantly higher among those taking antidepressants (odds ratio = 4.7), iron supplements (OR = 4.1) or narcotic analgesics (OR = 2.4). Those taking antidepressants at both ages 26 and 32 years had 22 times the odds of reporting xerostomia.
CONCLUSION
Xerostomia may be a problem for a sizeable minority of young adults.
目的
描述三十出头成年人中口干症的患病率及其相关因素，尤其关注药物暴露这一潜在风险因素。
材料与方法
在一项长期前瞻性队列研究中，对32岁的参与者进行口干症患病率及其相关因素的调查。约950名个体在26岁和32岁时接受评估，两次评估时均记录所服用药物。
结果
口干症的患病率为10.0%（无明显性别差异），在服用抗抑郁药（比值比=4.7）、铁补充剂（比值比=4.1）或麻醉性镇痛药（比值比=2.4）的人群中显著更高。在26岁和32岁时均服用抗抑郁药的人群报告口干症的几率是其他人的22倍。
结论
口干症可能是相当一部分年轻成年人面临的问题。
Zotero 插件