Holak H M, Holak N H, Schenk C, Olinger A, Holak S A
Augenpraxisklinik im Rudolf-Virchow-Arztehaus, Heckenstrasse 48, 38226 Salzgitter.
Ophthalmologe. 2006 Sep;103(9):798-805. doi: 10.1007/s00347-006-1374-z.
The course of Purtscher's retinopathy (PR) or Purtscher-like retinopathy (P-lR) is dependent on time, length, and expression of confluent cotton-wool spots. To correlate the course of the disease with findings of optical coherence tomography (OCT), we present two extreme courses of PR and P-lR.
Complete ophthalmological examination plus electroretinography (ERG) and OCT were performed. In the first case the follow-up was carried out until complete resorption of the edema and in the second case 8 years after the occurrence of P-lR.
An increase of the central retinal thickness (308-430 microm was observed during the acute phase of PR. Normalization of visual acuity and central retinal thickness to 210-273 microm with an ERG within normal limits (35 ms) was achieved after 8 weeks. In the course of P-lR the marked edema was visible even after 6 months and a markedly reduced neuroretina (112-120 microm) was measured after 8 years.
Retinal thickness analysis correlates well with organic functions in the cases of PR or P-lR. Fast reduction of the edema was associated with a good prognosis for visual acuity.
普尔夏视网膜病变（PR）或类普尔夏视网膜病变（P-lR）的病程取决于融合性棉絮斑的时间、范围及表现。为将疾病病程与光学相干断层扫描（OCT）结果相关联，我们展示了PR和P-lR的两种极端病程。
进行了全面的眼科检查以及视网膜电图（ERG）和OCT检查。第一例随访至水肿完全吸收，第二例在P-lR发生8年后进行检查。
PR急性期观察到中心视网膜厚度增加（308 - 430微米）。8周后视力和中心视网膜厚度恢复正常，分别为210 - 273微米，ERG在正常范围内（35毫秒）。在P-lR病程中，即使6个月后仍可见明显水肿，8年后测量神经视网膜厚度明显降低（112 - 120微米）。
在PR或P-lR病例中，视网膜厚度分析与器官功能密切相关。水肿快速消退与视力预后良好相关。
