Meyer J, Preusser P, Bünte H
Klinik und Poliklinik für Allgemeine Chirurgie, Westfälischen Wilhelms-Universität Münster, Bundesrepublik Deutschland.
Zentralbl Chir. 1991;116(15):917-21.
During the period from 1987-1990 152 patients underwent a Whipple procedure at the Department of General Surgery of Münster University Hospital. 27 operations were performed for chronic pancreatitis (17.8%), 52 for pancreatic (34.2%) and 73 (48.0%) for ampullary carcinoma. All patients received Somatostatin (6 mg/24 h) postoperatively for five days. These patients were compared with those of a former series who were identically operated but did not receive Somatostatin. In-hospital-mortality was reduced from 10.7% to 4.6%. Additionally the frequency of postoperative pancreatic fistulas was reduced among the nonlethal complications.
1987年至1990年期间，152例患者在明斯特大学医院普通外科接受了惠普尔手术。其中，因慢性胰腺炎接受手术的有27例（17.8%），因胰腺癌接受手术的有52例（34.2%），因壶腹癌接受手术的有73例（48.0%）。所有患者术后均接受生长抑素（6毫克/24小时）治疗，持续五天。将这些患者与之前一组接受相同手术但未接受生长抑素治疗的患者进行比较。住院死亡率从10.7%降至4.6%。此外，在非致命性并发症中，术后胰瘘的发生率也有所降低。
