Sihvola Elina, Keski-Rahkonen Anna, Dick Danielle M, Pulkkinen Lea, Rose Richard J, Marttunen Mauri, Kaprio Jaakko
Department of Public Health, University of Helsinki, Finland.
J Affect Disord. 2007 Jan;97(1-3):211-8. doi: 10.1016/j.jad.2006.06.019. Epub 2006 Jul 14.
Depressions that fail to meet the diagnostic criteria for major depressive disorder (MDD) may be underdiagnosed and undertreated in adolescent population. Traditionally, they are not considered as serious conditions and the phenomenological nature and clinical correlates of these disorders are largely unknown. In the present study, we used a large, representative and age-standardized sample of adolescents to examine the phenomenology and clinical correlates of minor depression, a poorly understood condition included in the category of Depressive Disorder Not Otherwise Specified in Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition-Text Revised (DSM-IV-TR).
909 girls and 945 boys, with mean age of 14, were interviewed by professionals using the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA).
Although clearly milder condition than MDD, minor depression was associated with marked suicidal thoughts, plans and attempts, recurrences and a high degree of comorbidity. At this early age, despite that 14% of adolescents under 15 had suffered from depressive conditions with severe clinical implications, most of them failing to meet the diagnostic threshold for MDD, only 1.7% had received any psychiatric treatment. 40% of depressive adolescents who had attempted suicide had no contact with mental health services.
Analyzed in a cross-sectional setting, no conclusions about long-term implications could be made.
The results highlight the clinical and public health significance of non-MDD depressions, e.g. minor depression, which need to be more carefully identified and treated at early age.
未达到重度抑郁症(MDD)诊断标准的抑郁症在青少年人群中可能未得到充分诊断和治疗。传统上,这些抑郁症不被视为严重疾病,其现象学本质和临床关联在很大程度上尚不明确。在本研究中,我们使用了一个具有代表性且经过年龄标准化的大型青少年样本,来研究轻度抑郁症的现象学和临床关联。轻度抑郁症是一种理解不足的病症,被纳入《精神疾病诊断与统计手册(第四版修订版)》(DSM-IV-TR)中“未另行规定的抑郁障碍”类别。
909名女孩和945名男孩,平均年龄为14岁,由专业人员使用酒精中毒遗传学半结构化评估(SSAGA)进行访谈。
尽管明显比重度抑郁症症状轻,但轻度抑郁症与明显的自杀念头、计划和企图、复发以及高度共病相关。在这个早期年龄段,尽管14%的15岁以下青少年患有具有严重临床意义的抑郁病症,其中大多数未达到重度抑郁症的诊断阈值,但只有1.7%的人接受过任何精神科治疗。40%有自杀企图的抑郁青少年未与心理健康服务机构接触。
在横断面研究中进行分析,无法得出关于长期影响的结论。
研究结果突出了非重度抑郁症(如轻度抑郁症)的临床和公共卫生意义,这类抑郁症在早期需要更仔细地识别和治疗。