Gao Y Z, van Alphen H A, Kamphorst W
Department of Neurosurgery, Free University Hospital, Amsterdam, The Netherlands.
Neurol Res. 1991 Sep;13(3):189-93. doi: 10.1080/01616412.1991.11739989.
In this study we applied the technique described in the previous paper (see pp. 103-106 of previous issue (1991); 13(2)) to rats with experimental saccular aneurysms. We found that the mean sizes and some growth ratios of experimental aneurysms were significantly larger in the intermittent blood pressure elevation groups than in the control groups. The increase of growth ratios was proportional to the number of transient blood pressure elevations. The morphological structure of these saccular aneurysms showed that the regenerative processes in the aneurysm wall had obviously been interfered with in animals with intermittent blood pressure elevation. The effective mechanism of this influential factor is discussed.
在本研究中，我们将上一篇论文（见前一期（1991年）第103 - 106页；第13卷第2期）中描述的技术应用于患有实验性囊状动脉瘤的大鼠。我们发现，间歇性血压升高组实验性动脉瘤的平均大小和一些生长率显著大于对照组。生长率的增加与短暂性血压升高的次数成正比。这些囊状动脉瘤的形态结构表明，在间歇性血压升高的动物中，动脉瘤壁的再生过程明显受到了干扰。本文讨论了这一影响因素的作用机制。
