Mavrogiannis M, Ellis J S, Seymour R A, Thomason J M
School of Dental Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK.
J Clin Periodontol. 2006 Sep;33(9):677-82. doi: 10.1111/j.1600-051X.2006.00968.x. Epub 2006 Jul 20.
The aim of the present study was to evaluate the efficacy of three different surgical techniques in both the management and effect upon rate of overgrowth recurrence of drug-induced gingival overgrowth (DIGO).
Two cohorts of patients who required surgical correction of their DIGO participated in the study. After baseline periodontal measures (plaque index, gingival inflammation and probing pocket depths), the patients underwent surgery. A split-mouth, crossover design was used to compare conventional gingivectomy with flap surgery (n=27), and conventional gingivectomy with laser excision (n=23). The main outcome variable was the rate of recurrence of DIGO following surgery.
At 6 months, there was significantly less recurrence (p=0.05) in patients treated with laser excision, compared with those treated by conventional gingivectomy. The differences in rate of recurrence of DIGO were also reflected in changes in several periodontal parameters. Flap surgery offered no advantage over conventional gingivectomy with respect to the rate of recurrence.
DIGO can be managed by a variety of techniques. Laser excision results in a reduced rate of recurrence.
本研究旨在评估三种不同手术技术在药物性牙龈增生（DIGO）的治疗及对其过度生长复发率的影响方面的疗效。
两组需要对DIGO进行手术矫正的患者参与了本研究。在进行基线牙周测量（菌斑指数、牙龈炎症和探诊袋深度）后，患者接受手术。采用双侧交叉设计比较传统牙龈切除术与翻瓣手术（n = 27），以及传统牙龈切除术与激光切除术（n = 23）。主要结局变量是手术后DIGO的复发率。
6个月时，与接受传统牙龈切除术的患者相比，接受激光切除术的患者复发率显著更低（p = 0.05）。DIGO复发率的差异也反映在几个牙周参数的变化上。在复发率方面，翻瓣手术与传统牙龈切除术相比没有优势。
DIGO可以通过多种技术进行治疗。激光切除术可降低复发率。
