Meier C, Keller I S, Pfiffner R, Labler L, Trentz O, Pfammatter T
Division of Trauma Surgery, University Hospital Zurich, Switzerland.
Eur J Vasc Endovasc Surg. 2006 Nov;32(5):589-95. doi: 10.1016/j.ejvs.2006.04.040. Epub 2006 Jul 20.
Prophylactic vena cava filters (VCF) are efficient in preventing pulmonary embolism. Filter retrieval avoids the potential long-term complications of permanent VCF. Clinical evaluation was focused on filter-related complications and feasibility of retrieval in high-risk trauma patients.
Analysis of single-institution consecutive case series of patients who received a prophylactic OptEase VCF after multiple trauma between 08/2003 and 12/2004. Data were collected prospectively.
A total of 37 OptEase filters were inserted prophylactically after multiple trauma (median patient age 35 years, range, 17-73 years, median ISS 41, range, 17-59). All patients had contraindications for pharmacological prophylaxis for thromboembolic events. 32 filters (86%) were retrieved after 16 days (range, 7-25 days). 12 of 33 filters (36%) demonstrated trapped clots/thrombosis within the filter structure on pre-retrieval cavography. Two patients received anticoagulation before filter retrieval due to filter thrombosis (6%). Symptomatic PE was observed in 1 patient (3%) 5 days after VCF retrieval. Minor caudal filter migration was observed in 1 patient (3%). Overall mortality was 3%.
Retrieval of the OptEase filter is safe and feasible. Temporary filter placement avoids possible long-term complications of permanent VCF. It is an efficient form of PE prophylaxis when temporary contraindications to anticoagulation are present.
预防性腔静脉滤器(VCF)在预防肺栓塞方面有效。滤器取出可避免永久性VCF的潜在长期并发症。临床评估集中于滤器相关并发症以及高危创伤患者取出滤器的可行性。
分析2003年8月至2004年12月间因多发伤接受预防性OptEase VCF的单机构连续病例系列。数据前瞻性收集。
多发伤后共预防性植入37枚OptEase滤器(患者中位年龄35岁,范围17 - 73岁,中位损伤严重度评分[ISS]41,范围17 - 59)。所有患者均有血栓栓塞事件药物预防的禁忌证。32枚滤器(86%)在16天(范围7 - 25天)后取出。33枚滤器中有12枚(36%)在取出前的腔静脉造影中显示滤器结构内有血栓形成。2例患者因滤器血栓形成在取出滤器前接受了抗凝治疗(6%)。在VCF取出后5天,1例患者(3%)出现有症状的肺栓塞。1例患者(3%)观察到滤器轻微尾端移位。总体死亡率为3%。
OptEase滤器取出安全可行。临时放置滤器可避免永久性VCF可能的长期并发症。当存在抗凝治疗的临时禁忌证时,它是预防肺栓塞的一种有效方式。