Wehrenberg-Klee Eric, Stavropoulos S William
Department of Internal Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Semin Intervent Radiol. 2012 Mar;29(1):29-35. doi: 10.1055/s-0032-1302449.
Over the past several years there has been a rapid increase in the number of inferior vena cava (IVC) filters placed for primary thromboprophylaxis. Increased use has occurred in settings where other methods of thromboprophylaxis are viewed to be inadequate, technically challenging, or that place patients at an unacceptably high bleeding risk. These clinical services include trauma, bariatric surgery, neurosurgery, cancer, intensive care unit populations, and patients with a relative contraindication to anticoagulation. We review the studies to date addressing filter placement for these indications. Although preliminary data are promising, the patient populations most likely to benefit from prophylactic IVC filter placement have not been well defined, and randomized studies demonstrating efficacy have not been conducted. Moving forward, it will be critical to accomplish these two tasks if IVC filters are to continue to have a role in primary thromboprophylaxis.
在过去几年中，为进行一级血栓预防而植入下腔静脉（IVC）滤器的数量迅速增加。在其他血栓预防方法被认为不足、技术上具有挑战性或使患者面临不可接受的高出血风险的情况下，IVC滤器的使用有所增加。这些临床情况包括创伤、减肥手术、神经外科手术、癌症、重症监护病房患者以及对抗凝有相对禁忌证的患者。我们回顾了迄今为止针对这些适应证进行滤器植入的研究。尽管初步数据很有前景，但最有可能从预防性IVC滤器植入中获益的患者群体尚未明确界定，且尚未开展证明其有效性的随机研究。展望未来，如果IVC滤器要继续在一级血栓预防中发挥作用，完成这两项任务至关重要。
