Tang W M, To K Y
Forensic Science Division, Hong Kong Government Laboratory, Homantin Government Offices, 88 Chung Hau Street, Kowloon, Hong Kong SAR, China.
Forensic Sci Int. 2006 Oct 16;162(1-3):64-5. doi: 10.1016/j.forsciint.2006.06.018. Epub 2006 Jul 24.
X-chromosomal markers are particularly useful for solving complex problems relating to kinship and deficiency paternity analysis. In the present study, population genetics data of four X-chromosomal short tandem repeats (STRs) DXS8378, HPRTB, DXS7423 and DXS7132 were obtained by analyzing 500 unrelated Chinese individuals (250 males and 250 females). Population genetics data obtained from the Chinese were compared with those of the Asian and European population. Mutations in X-chromosomal markers were analyzed based on a total of 61 proven father-child and 45 proven mother-child pairs.
X染色体标记对于解决与亲属关系和亲子关系缺失分析相关的复杂问题特别有用。在本研究中，通过分析500名无血缘关系的中国人（250名男性和250名女性），获得了四个X染色体短串联重复序列（STR）DXS8378、HPRTB、DXS7423和DXS7132的群体遗传学数据。将中国人的群体遗传学数据与亚洲和欧洲人群的数据进行了比较。基于总共61对已证实的父子对和45对已证实的母子对，分析了X染色体标记中的突变。
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