Barbati A, Anceschi M M, Broccucci L, Cosmi E V
Institute of Gynecology and Obstetrics, University of Perugia, Italy.
Am J Obstet Gynecol. 1990 Jan;162(1):266-8. doi: 10.1016/0002-9378(90)90862-2.
CA 125 was measured in the medium of human amnion cells in primary culture after confluence. The antigen accumulated as a function of time with a median value of 1897 U/mg protein after 7 days in culture. CA 125 was detectable by immunoperoxidase staining in the cells, which supports the possibility that amnion cells play a role as a source of the CA 125 found in the amniotic fluid.
融合后原代培养的人羊膜细胞培养基中检测了CA 125。抗原随时间积累，培养7天后蛋白质的中位值为1897 U/mg。通过免疫过氧化物酶染色可在细胞中检测到CA 125，这支持了羊膜细胞作为羊水内发现的CA 125来源发挥作用的可能性。
