Khoosal Dipen, Goldman Ran D
Hospital for Sick Children, Toronto, Ont.
Can Fam Physician. 2006 Jul;52(7):855-6.
A few of my patients have been told to use vitamin E cream after surgery or repair of a laceration. What is the evidence for this suggestion, and is this treatment suitable for all patients?
Vitamin E is the main lipid-soluble antioxidant in the skin. Several anecdotal reports have suggested that topical use of vitamin E cream can reduce scar formation. Current evidence from the literature, however, does not support that proposition. In fact, studies report some adverse effects with use of vitamin E. Further research is needed before application of vitamin E cream becomes the standard of care.
我的几位患者被告知在手术后或伤口缝合后使用维生素E乳膏。这一建议的依据是什么,这种治疗方法是否适用于所有患者?
维生素E是皮肤中主要的脂溶性抗氧化剂。一些轶事报道表明,局部使用维生素E乳膏可减少瘢痕形成。然而,目前文献中的证据并不支持这一观点。事实上,研究报告了使用维生素E的一些不良反应。在维生素E乳膏成为标准治疗方法之前,还需要进一步研究。