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由肌动蛋白聚合驱动的微绒毛的动力学与形态学

Dynamics and morphology of microvilli driven by actin polymerization.

作者信息

Gov Nir S

机构信息

Department of Chemical Physics, The Weizmann Institute of Science, P.O.B. 26, Rehovot, Israel 76100.

出版信息

Phys Rev Lett. 2006 Jul 7;97(1):018101. doi: 10.1103/PhysRevLett.97.018101. Epub 2006 Jul 5.

Abstract

Many different cell types have dynamic protrusions, called microvilli, on their surface. We model these structures as arising from the balance between the force of actin polymerization and the restoring force of the membrane. From this simple model we calculate the distribution function of microvilli heights for several cells. We further describe the phase diagram and the resulting morphology of the microvilli aggregates on the cell surface.

摘要

许多不同类型的细胞在其表面具有动态突起,称为微绒毛。我们将这些结构建模为由肌动蛋白聚合力和膜的恢复力之间的平衡产生。从这个简单模型中,我们计算了几种细胞微绒毛高度的分布函数。我们进一步描述了相图以及细胞表面微绒毛聚集体的最终形态。

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