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腰椎管狭窄症术后临床结局的术前预测因素:系统评价

Preoperative predictors for postoperative clinical outcome in lumbar spinal stenosis: systematic review.

作者信息

Aalto Timo J, Malmivaara Antti, Kovacs Francisco, Herno Arto, Alen Markku, Salmi Liisa, Kröger Heikki, Andrade Juan, Jiménez Rosa, Tapaninaho Antti, Turunen Veli, Savolainen Sakari, Airaksinen Olavi

机构信息

Department of Surgery, Kuopio University, Kuopio, Finland.

出版信息

Spine (Phila Pa 1976). 2006 Aug 15;31(18):E648-63. doi: 10.1097/01.brs.0000231727.88477.da.

Abstract

STUDY DESIGN

Systematic review.

OBJECTIVE

To define preoperative factors predicting clinical outcome after lumbar spinal stenosis (LSS) surgery.

SUMMARY OF BACKGROUND DATA

LSS is the most common reason requiring lumbar spine surgery in adults older than 65 years. There are no published systematic reviews on this topic.

METHODS

A literature search was done until April 30, 2005. Included were randomized controlled or controlled trials or prospective studies dealing with operated LSS. The preoperative predictors had to be presented. Included articles were assessed as high-quality (HQ) and low-quality studies. The predictors in HQ studies were considered as the main results.

RESULTS

A total of 21 articles were included. Depression and walking capacity were predictors according to 2 HQ studies. Predictors reported in 1 HQ study were cardiovascular/overall comorbidity, disorder influencing walking ability, self-rated health, income, severity of central stenosis, and scoliosis.

CONCLUSION

Depression, cardiovascular comorbidity, disorder influencing walking ability, and scoliosis predicted poorer subjective outcome. Better walking ability, self-rated health, higher income, less overall comorbidity, and pronounced central stenosis predicted better subjective outcome. Male gender and younger age predicted better postoperative walking ability. The predictive value may be outcome specific; thus, the use of all relevant outcome measures is recommended when studying predictors of LSS.

摘要

研究设计

系统评价。

目的

确定预测腰椎管狭窄症(LSS)手术后临床结局的术前因素。

背景资料总结

LSS是65岁以上成年人需要进行腰椎手术的最常见原因。关于该主题尚无已发表的系统评价。

方法

进行文献检索至2005年4月30日。纳入的是涉及接受手术的LSS的随机对照试验、对照试验或前瞻性研究。必须呈现术前预测因素。纳入的文章被评估为高质量(HQ)和低质量研究。HQ研究中的预测因素被视为主要结果。

结果

共纳入21篇文章。根据两项HQ研究,抑郁和步行能力是预测因素。一项HQ研究报告的预测因素为心血管/总体合并症、影响步行能力的疾病、自我评定的健康状况、收入、中央椎管狭窄的严重程度和脊柱侧弯。

结论

抑郁、心血管合并症、影响步行能力的疾病和脊柱侧弯预示主观结局较差。较好的步行能力、自我评定的健康状况、较高的收入、较少的总体合并症和明显的中央椎管狭窄预示主观结局较好。男性和较年轻年龄预示术后步行能力较好。预测价值可能因结局而异;因此,在研究LSS的预测因素时,建议使用所有相关的结局指标。

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