囊性纤维化肺部炎症的新见解
New insights into pulmonary inflammation in cystic fibrosis.
作者信息
Rao S, Grigg J
机构信息
Department of Respiratory Medicine and Cystic Fibrosis, Birmingham Children's Hospital NHS Trust, Steelhouse Lane, Birmingham B4 6NH, UK.
出版信息
Arch Dis Child. 2006 Sep;91(9):786-8. doi: 10.1136/adc.2004.069419.
Abstract
Persistent lower airway infection with inflammation is the major cause of morbidity and mortality in cystic fibrosis. This review examines the recent advances in the understanding of airway inflammation in cystic fibrosis, and focuses on the evidence that pulmonary inflammation is, under some circumstances, disassociated from infection, and the potential implications for therapeutic intervention.
摘要
持续性下呼吸道感染伴炎症是囊性纤维化发病和死亡的主要原因。本综述探讨了在理解囊性纤维化气道炎症方面的最新进展，并着重于以下证据：在某些情况下，肺部炎症与感染无关，以及这对治疗干预的潜在影响。
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本文引用的文献
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Lower airway inflammation in infants with cystic fibrosis detected by newborn screening.通过新生儿筛查检测到的囊性纤维化婴儿的下呼吸道炎症。
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Clin Exp Immunol. 2004 Dec;138(3):507-16. doi: 10.1111/j.1365-2249.2004.02637.x.
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