Tang Yee-Chin, Katsuma Shoji, Fujimoto Shinji, Hiromoto Sachiko
Division of Materials and Manufacturing Science, Graduate School of Engineering, 2-1 Yamada-oka, Suita, Osaka University, Osaka 565-0871, Japan.
Acta Biomater. 2006 Nov;2(6):709-15. doi: 10.1016/j.actbio.2006.06.003. Epub 2006 Aug 28.
The electrochemical corrosion behaviour of Type 304 and 316L stainless steels was studied in Hanks' solution, Eagle's minimum essential medium (MEM), serum containing medium (MEM with 10% of fetal bovine serum) without cells, and serum containing medium with cells over a 1-week period. Polarization resistance measurements indicated that the stainless steels were resistant to Hanks' and MEM solutions. Type 304 was more susceptible to pitting corrosion than Type 316L in Hanks' and MEM solutions. The uniform corrosion resistance of stainless steels, determined by R(p), was lower in culturing medium than in Hanks' and MEM. The low corrosion resistance was due to surface passive film with less protective to reveal high anodic dissolution rate. When cells were present, the initial corrosion resistance was low, but gradually increased after 3 days, consistent with the trend of cell coverage. The presence of cells was found to suppress the cathodic reaction, that is, oxygen reduction, and increase the uniform corrosion resistance as a consequence. On the other hand, both Type 304 and 316L stainless steels became more susceptible to pitting corrosion when they were covered with cells.
研究了304型和316L型不锈钢在汉克斯溶液、伊格尔氏最低限度基本培养基（MEM）、无细胞的含血清培养基（含10%胎牛血清的MEM）以及含细胞的含血清培养基中为期1周的电化学腐蚀行为。极化电阻测量表明，不锈钢对汉克斯溶液和MEM溶液具有抗性。在汉克斯溶液和MEM溶液中，304型不锈钢比316L型不锈钢更容易发生点蚀。通过R(p)测定的不锈钢均匀耐蚀性在培养基中低于在汉克斯溶液和MEM中。耐蚀性低是由于表面钝化膜的保护性较差，导致阳极溶解速率较高。当有细胞存在时，初始耐蚀性较低，但3天后逐渐增加，这与细胞覆盖趋势一致。发现细胞的存在会抑制阴极反应，即氧还原，并因此提高均匀耐蚀性。另一方面，当304型和316L型不锈钢被细胞覆盖时，它们更容易发生点蚀。
