Alvarez Kelly, Hyun Soong-Keun, Fujimoto Shinji, Nakajima Hideo
The Institute of Scientific and Industrial Research, Osaka University, Ibaraki, Osaka, 567-0047, Japan.
J Mater Sci Mater Med. 2008 Nov;19(11):3385-97. doi: 10.1007/s10856-008-3458-6. Epub 2008 Jun 11.
The corrosion behavior of three kinds of austenitic high nitrogen Lotus-type porous Ni-free stainless steels was examined in acellular simulated body fluid solutions and compared with type AISI 316L stainless steel. The corrosion resistance was evaluated by electrochemical techniques, the analysis of released metal ions was performed by inductively coupled plasma mass spectrometry (ICP-MS) and the cytotoxicity was investigated in a culture of murine osteoblasts cells. Total immunity to localized corrosion in simulated body fluid (SBF) solutions was exhibited by Lotus-type porous Ni-free stainless steels, while Lotus-type porous AISI 316L showed very low pitting corrosion resistance evidenced by pitting corrosion at a very low breakdown potential. Additionally, Lotus-type porous Ni-free stainless steels showed a quite low metal ion release in SBF solutions. Furthermore, cell culture studies showed that the fabricated materials were non-cytotoxic to mouse osteoblasts cell line. On the basis of these results, it can be concluded that the investigated alloys are biocompatible and corrosion resistant and a promising material for biomedical applications.
研究了三种奥氏体高氮莲花型无镍多孔不锈钢在脱细胞模拟体液溶液中的腐蚀行为,并与AISI 316L型不锈钢进行了比较。通过电化学技术评估耐腐蚀性,采用电感耦合等离子体质谱(ICP-MS)分析释放的金属离子,并在小鼠成骨细胞培养物中研究细胞毒性。莲花型无镍多孔不锈钢在模拟体液(SBF)溶液中表现出对局部腐蚀的完全免疫,而莲花型多孔AISI 316L在非常低的击穿电位下发生点蚀,显示出非常低的耐点蚀性。此外,莲花型无镍多孔不锈钢在SBF溶液中的金属离子释放量相当低。此外,细胞培养研究表明,所制备的材料对小鼠成骨细胞系无细胞毒性。基于这些结果,可以得出结论,所研究的合金具有生物相容性和耐腐蚀性,是一种有前途的生物医学应用材料。