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[超声生物显微镜测量的睫状体长度与葡萄膜炎的病程、部位及严重程度之间的关系]

[The relationship between the length of ciliary processes as measured by ultrasound biomicroscopy and the duration, localization and severity of uveitis].

作者信息

da Costa Daniella Socci, Lowder Careen, de Moraes Haroldo Vieira, Oréfice Fernando

机构信息

Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

出版信息

Arq Bras Oftalmol. 2006 May-Jun;69(3):383-8. doi: 10.1590/s0004-27492006000300018.

Abstract

PURPOSE

To determine the relationship between the length of ciliary processes as measured by ultrasound biomicroscopy and the duration, localization and severity of uveitis.

METHODS

We analyzed in this prospective study, 58 individuals including patients with different stages of uveitis and normal patients (112 eyes including 18 normal), between August 2001 and August 2002, at the Cleveland Clinic Foundation, Ohio, USA. All patients were referred to ultrasound biomicroscopy by the Uveitis Department, after a complete ophthalmological examination. A 50 MHz-transducer UBM model 840 (Zeiss-Humphrey) was used under topical anesthesia and immersion technique.

RESULTS

The most frequent etiology was idiophatic uveitis (27.8%). Recurrent, aggressive and diffuse uveitis lead to significant damage of the ciliary processes. The most significant loss of the ciliary processes was found in the inferior quadrant and the highest in normal patients and in the temporal quadrant. Hypotonic eyes have their ciliary processes reduced.

CONCLUSIONS

Ultrasound biomicroscopy has proved to be useful in evaluating anatomical changes of ciliary processes in uveitis and in ocular hypotony, and provides a basis to, make recommendations regarding baseline screening of uveitis patients. Patients who are found to have atrophy of the ciliary processes may need a more aggressive treatment for any signs of inflammation to prevent further damage and eventual hypotony.

摘要

目的

通过超声生物显微镜测量睫状体的长度,并确定其与葡萄膜炎的病程、部位及严重程度之间的关系。

方法

2001年8月至2002年8月期间,在美国俄亥俄州克利夫兰诊所基金会,我们对58例患者进行了这项前瞻性研究,其中包括处于不同葡萄膜炎阶段的患者以及正常患者(共112只眼,其中18只为正常眼)。所有患者在完成全面眼科检查后,由葡萄膜炎科转诊至超声生物显微镜检查。在表面麻醉和浸没技术下,使用50MHz换能器的840型超声生物显微镜(蔡司 - 汉弗莱)。

结果

最常见的病因是特发性葡萄膜炎(27.8%)。复发性、侵袭性和弥漫性葡萄膜炎会导致睫状体严重受损。睫状体最显著的缺失见于下象限,而在正常患者和颞象限中最高。低眼压眼的睫状体有所减少。

结论

超声生物显微镜已被证明在评估葡萄膜炎和低眼压时睫状体的解剖学变化方面很有用,并为对葡萄膜炎患者进行基线筛查提出建议提供了依据。发现有睫状体萎缩的患者,对于任何炎症迹象可能需要更积极的治疗,以防止进一步损害和最终导致低眼压。

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