Department of Ophthalmology, Clinical County Emergency Hospital, Brăila, Romania.
Department of Ophthalmology, "Grigore T. Popa" University of Medicine and Pharmacy, Iaşi, Romania.
Rom J Ophthalmol. 2023 Jul-Sep;67(3):238-243. doi: 10.22336/rjo.2023.40.
To observe the ocular structural changes in active and inactive uveitis patients. This retrospective study involved 30 patients (32 eyes) with anterior and intermediate uveitis cases and 54 eyes of 54 cases in a control group, who were admitted to the Ophthalmology Department at Trakya University. In the study group, 14 patients were females, 16 patients were males and in the control group 26 volunteers were females, and 28 volunteers were male of the 54 volunteers. Anterior chamber depth, axial length, intraocular pressure, lens thickness, central corneal thickness, steep and flat values in keratometry, corrected visual acuity in both eyes, anterior chamber cells, and vitreous cells were measured and compared between three groups (two uveitis groups - active and inactive - and control group). In the comparison of the median values of axial length, central corneal thickness, and steep and flat values of keratometry, the values of the patients with active uveitis were higher than the ones in the control group in each parameter, but no significant difference was observed. The anterior chamber depth parameter value was higher, the lens thickness value was lower in patients with active uveitis than the values in the control group and the differences were statistically significant (p<0,05). No significant structural differences in the values of the active and inactive group patients (p>0,05) were observed. Only lens thickness and anterior chamber depth parameters were statistically significant in patients with active uveitis, compared with the inactive uveitis group. Anterior chamber depth measurement values were higher and lens thickness measurement values were lower in patients with active uveitis when compared with the control group. AAU = Acute anterior uveitis, CAU = Chronic Anterior Uveitis, AC = Anterior Chamber, IOP = Intraocular Pressure, IVCM = Confocal Microscopy, AS-OCT = Anterior Segment Optical Coherence Tomography, UBM = Ultrasound Biomicroscopy, LFP = Laser Flare Photometry, KP = Keratic Precipitates, OCT = Optical Coherence Tomography, AL = Axial Length, ACD = Anterior Chamber Depth, LT = Lens Thickness, CCT = Central Corneal Thickness, Ks = Steep Value of Keratometry, Kf = Flat Value of Keratometry, AUP = Active Uveitis Patients, IUP = Inactive Uveitis Patients, SUN = Standardization of Uveitis Nomenclature.
观察活动期和非活动期葡萄膜炎患者的眼部结构变化。这项回顾性研究纳入了 30 名（32 只眼）前葡萄膜炎和中间葡萄膜炎患者，以及 54 名对照组患者（54 只眼），所有患者均在土耳其特拉基大学眼科就诊。研究组中，14 名女性，16 名男性；对照组中，26 名女性志愿者，28 名男性志愿者。测量并比较三组（两组葡萄膜炎患者——活动期和非活动期，以及对照组）的前房深度、眼轴长度、眼内压、晶状体厚度、中央角膜厚度、角膜曲率计的陡峭值和平坦值、双眼矫正视力、前房细胞和玻璃体细胞。在比较活动期葡萄膜炎患者的眼轴长度、中央角膜厚度和角膜曲率计陡峭和平坦值的中位数时，每个参数中活动期葡萄膜炎患者的值均高于对照组，但无显著差异。活动期葡萄膜炎患者的前房深度参数值较高，晶状体厚度值较低，与对照组相比差异有统计学意义（p<0.05）。活动期和非活动期患者组（p>0.05）的结构差异无统计学意义。与非活动期葡萄膜炎组相比，仅活动期葡萄膜炎患者的晶状体厚度和前房深度参数有统计学意义。与对照组相比，活动期葡萄膜炎患者的前房深度测量值较高，晶状体厚度测量值较低。AAU = 急性前葡萄膜炎，CAU = 慢性前葡萄膜炎，AC = 前房，IOP = 眼内压，IVCM = 共焦显微镜，AS-OCT = 眼前节光学相干断层扫描，UBM = 超声生物显微镜，LFP = 激光闪烁光度计，KP = 角膜后沉着物，OCT = 光学相干断层扫描，AL = 眼轴长度，ACD = 前房深度，LT = 晶状体厚度，CCT = 中央角膜厚度，Ks = 角膜曲率计陡峭值，Kf = 角膜曲率计平坦值，AUP = 活动期葡萄膜炎患者，IUP = 非活动期葡萄膜炎患者，SUN = 葡萄膜炎命名标准化。
