Serour F, Somekh E
Clalit Health Services, Holon, Israel.
Eur J Pediatr Surg. 2003 Aug;13(4):219-23. doi: 10.1055/s-2003-42237.
Warts are difficult to treat and none of the several modes of treatment suggested for their cure has been proven to be the most effective. We evaluated the efficacy of a modification of the CO (2) laser technique for recalcitrant warts in pediatric patients.
During a period of 5 years, 40 consecutive pediatric patients (average age: 12.7 +/- 2.8 years) were treated by CO (2) laser for 54 recalcitrant warts. Previous treatments were caustic and/or surgical procedures (average 2.7 procedures). Local anesthesia or digital block was performed in all patients, with intravenous sedation in two patients. The laser was used at 5 W in super-pulse mode throughout the procedure. The skin was cut with the focused laser beam in a circular fashion, about 5 mm around the wart, until all the layers of the skin down to the subcutaneous tissue were penetrated. The lesion was drawn aside and excised, using the laser beam as a scalpel. No curettage was used. The base of the wart was then vaporized with the laser in a defocused fashion, until a clean surgical field was obtained. Follow-up was weekly up to 1 month, and at 3, 6, and 12 months.
Warts were located on fingers (24 cases), in the plantar area (10 cases), on hands (9 cases), knees, and legs (4 cases each), arms (2 cases) and elbow (1 case). Twenty-seven patients (67.5 %) had a solitary wart and the other 13 children had multiple warts (up to 6) at one or more locations. Fingers were the most common location of multiple warts (10 cases). All patients underwent the procedure in one session. No case of intractable operative bleeding, local infection, or prolonged exudative drainage was encountered. One patient complained of severe transient postoperative pain. The healing time was 4 to 5 weeks. At 12 months, there was no recurrence of the warts. No significant or disabling scarring was noticed, but hypopigmentation was noted in 11 cases (27.5 %).
This technique provides a high success rate with minimal side effects and is well tolerated by young patients.
疣难以治疗,目前所建议的几种治疗方式中,尚无一种被证明是最有效的。我们评估了改良二氧化碳激光技术治疗儿科患者顽固性疣的疗效。
在5年期间,连续40例儿科患者(平均年龄:12.7±2.8岁)因54处顽固性疣接受二氧化碳激光治疗。先前的治疗方法为腐蚀性和/或外科手术(平均2.7次手术)。所有患者均实施局部麻醉或指神经阻滞,2例患者同时给予静脉镇静。整个手术过程中,激光以5瓦的超脉冲模式使用。用聚焦激光束以环形方式切割皮肤,围绕疣体约5毫米,直至穿透至皮下组织的所有皮肤层。将病变组织拨开,用激光束作为手术刀切除。未进行刮除术。然后用散焦的激光汽化疣体底部,直至获得干净的手术视野。随访至术后1个月每周进行,术后3个月、6个月和12个月时也进行随访。
疣体位于手指(24例)、足底区域(10例)、手部(9例)、膝盖和腿部(各4例)、手臂(2例)和肘部(1例)。27例患者(67.5%)有单个疣体,其他13名儿童在一个或多个部位有多个疣体(最多6个)。手指是多个疣体最常见的部位(10例)。所有患者均在一次手术中完成治疗。未出现难治性手术出血、局部感染或长期渗出性引流的病例。1例患者抱怨术后有严重的短暂疼痛。愈合时间为4至5周。12个月时,疣体无复发。未观察到明显或致残性瘢痕形成,但11例(27.5%)出现色素减退。
该技术成功率高,副作用小,年轻患者耐受性良好。