Harrington Greg S, Farias Dana, Davis Christine H, Buonocore Michael H
Department of Radiology, University of California at Davis, Sacramento, California, USA.
Hum Brain Mapp. 2007 May;28(5):450-9. doi: 10.1002/hbm.20286.
Drawing and writing are complex processes that require the synchronization of cognition, language, and perceptual-motor skills. Drawing and writing have both been utilized in the treatment of aphasia to improve communication. Recent research suggests that the act of drawing an object facilitated naming, whereas writing the word diminished accurate naming in individuals with aphasia. However, the relationship between object drawing and subsequent phonological output is unclear. Although the right hemisphere is characteristically mute, there is evidence from split-brain research that the right hemisphere can integrate pictures and words, likely via a semantic network. We hypothesized that drawing activates right hemispheric and left perilesional regions that are spared in aphasic individuals and may contribute to semantic activation that supports naming. Eleven right-handed subjects participated in a functional MRI (fMRI) experiment involving imagined drawing and writing and 6 of the 11 subjects participated in a second fMRI experiment involving actual writing and drawing. Drawing and writing produced very similar group activation maps including activation bilaterally in the premotor, inferior frontal, posterior inferior temporal, and parietal areas. The comparison of drawing vs. writing revealed significant differences between the conditions in areas of the brain known for language processing. The direct comparison between drawing and writing revealed greater right hemisphere activation for drawing in language areas such as Brodmann area (BA) 46 and BA 37.
绘画和书写是复杂的过程，需要认知、语言和感知运动技能的同步配合。绘画和书写都已被用于失语症的治疗以改善沟通。最近的研究表明，绘制物体的行为有助于命名，而书写单词则会降低失语症患者的准确命名能力。然而，物体绘画与随后的语音输出之间的关系尚不清楚。尽管右半球通常是沉默的，但来自裂脑研究的证据表明，右半球可能通过语义网络整合图片和单词。我们假设，绘画会激活失语症患者未受损的右半球和左侧病灶周围区域，并可能有助于支持命名的语义激活。11名右利手受试者参与了一项功能性磁共振成像（fMRI）实验，该实验涉及想象绘画和书写，其中11名受试者中的6名参与了另一项fMRI实验，该实验涉及实际书写和绘画。绘画和书写产生了非常相似的全组激活图，包括双侧运动前区、额下回、颞下后区和顶叶区域的激活。绘画与书写的比较揭示了在已知语言处理区域中不同条件之间的显著差异。绘画和书写的直接比较显示，在诸如布罗德曼区（BA）46和BA 37等语言区域，绘画时右半球的激活更强。
