Hove L, Holme B, Øgaard B, Willumsen T, Tveit A B
Faculty of Dentistry,University of Oslo, Oslo, Norway.
Caries Res. 2006;40(5):440-3. doi: 10.1159/000094291.
The purpose of this in vitro study was to compare the protective effect of TiF4, SnF2 and NaF (all 0.5 M F) on the development of erosion-like lesions in human dental enamel. Four enamel specimens from each of 6 extracted molars were polished and embedded in epoxy resin. The enamel surfaces of 3 specimens from each tooth were treated with the different fluoride solutions for 2 min. Following fluoride treatments, the specimens were immersed in 0.01 M HCl (pH 2.0), for 2, 4 and 6 min in order to mimic a gastric reflux situation. One specimen from each tooth was used as a control and was only exposed to acid. The etching depths (in micrometres) after 6 min were: TiF4 0.8 (SD 0.8), SnF2 3.5 (SD 0.7), NaF 5.3 (SD 0.4), and 7.0 (SD 0.3) for the control specimens. Compared to the control, TiF(4) protected the enamel surface from acid attack almost completely (88%), while SnF2 reduced the etch depth after 6 min by 50% and NaF by 25%.
这项体外研究的目的是比较四氟化钛(TiF4)、氟化亚锡(SnF2)和氟化钠(NaF)(均为0.5M氟化物)对人牙釉质中侵蚀样病变发展的保护作用。从6颗拔除的磨牙中各取4个牙釉质样本进行抛光,并嵌入环氧树脂中。每颗牙齿的3个样本的牙釉质表面用不同的氟化物溶液处理2分钟。氟化物处理后,将样本浸入0.01M盐酸(pH 2.0)中2、4和6分钟,以模拟胃反流情况。每颗牙齿的1个样本用作对照,仅暴露于酸中。6分钟后的蚀刻深度(以微米计)分别为:TiF4为0.8(标准差0.8),SnF2为3.5(标准差0.7),NaF为5.3(标准差0.4),对照样本为7.0(标准差0.3)。与对照相比,TiF4几乎完全保护牙釉质表面免受酸侵蚀(88%),而SnF2使6分钟后的蚀刻深度降低了50%,NaF降低了25%。