Hove Lene Hystad, Holme Børge, Young Alix, Tveit Anne Bjørg
Faculty of Dentistry, University of Oslo, Norway.
Acta Odontol Scand. 2007 Oct;65(5):259-64. doi: 10.1080/00016350701477581.
The aim of this study was to compare the protective effect of TiF(4), SnF(2), and NaF treatment on the development of erosion-like lesions in pellicle-covered human enamel.
Twelve human molars were each divided into 5 specimens, 4 of which were immersed in saliva for 2 h. Three pellicle-covered specimens from each tooth were treated with a TiF(4), SnF(2), or NaF solution (all 0.5 M F) for 2 min. Control specimens, one with and one without pellicle, were included. Immersion in acid (0.01 M HCl) was carried out stepwise (2+2+2+2 min). The etching depths (in microm) were measured using white light interferometry.
Compared with the control with pellicle, TiF(4) reduced enamel loss by 100% after 2 min and by 24% after 8 min of acid exposure. The corresponding values for SnF(2) were 45% and 14%. NaF provided no significant protection of the surface. The pellicle-covered specimens showed reduced lesion depths after 6 and 8 min compared to the controls without pellicle.
TiF(4) gave the best protection against acid attack. SnF(2) provided significant protection only after 2 min of acid exposure, while NaF had no significant protective effect.
本研究旨在比较四氟化钛（TiF₄）、氟化亚锡（SnF₂）和氟化钠（NaF）处理对覆盖有薄膜的人牙釉质中侵蚀样病变发展的保护作用。
将12颗人磨牙各分成5个样本，其中4个样本浸入唾液2小时。每颗牙齿的3个覆盖有薄膜的样本分别用四氟化钛、氟化亚锡或氟化钠溶液（均为0.5M F）处理2分钟。纳入对照样本，一个有薄膜，一个没有薄膜。逐步进行酸（0.01M HCl）浸泡（2 + 2 + 2 + 2分钟）。使用白光干涉测量法测量蚀刻深度（以微米为单位）。
与有薄膜的对照相比，四氟化钛在酸暴露2分钟后使牙釉质损失减少100%，在酸暴露8分钟后减少24%。氟化亚锡的相应值分别为45%和14%。氟化钠对表面没有显著的保护作用。与没有薄膜的对照相比，覆盖有薄膜的样本在6分钟和8分钟后的病变深度减小。
四氟化钛对酸侵蚀提供了最佳保护。氟化亚锡仅在酸暴露2分钟后提供显著保护，而氟化钠没有显著的保护作用。
