水泡性口炎病毒和脊髓灰质炎病毒中特定单密码子位点的突变频率仅能通过化学诱变略有增加。
Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis.
作者信息
Holland J J, Domingo E, de la Torre J C, Steinhauer D A
机构信息
Institute of Molecular Genetics, University of California, San Diego, La Jolla 92093.
出版信息
J Virol. 1990 Aug;64(8):3960-2. doi: 10.1128/JVI.64.8.3960-3962.1990.
Abstract
Mutagenesis by a variety of chemical mutagens conferred only 1.1- to 2.8-fold increases in mutation frequencies at defined single base sites in vesicular stomatitis virus and poliovirus.
摘要
多种化学诱变剂诱导的诱变作用，仅使水疱性口炎病毒和脊髓灰质炎病毒特定单碱基位点的突变频率提高了1.1至2.8倍。
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本文引用的文献
1
Mutation of type 3 poliovirus with nitrous acid.用亚硝酸对3型脊髓灰质炎病毒进行诱变。
Virology. 1962 May;17:99-109. doi: 10.1016/0042-6822(62)90086-7.
2
Induction of Newcastle disease virus mutants with nitrous acid.用亚硝酸诱导新城疫病毒突变体。
Virology. 1961 Apr;13:402-8. doi: 10.1016/0042-6822(61)90270-7.
3
Production of mutations in tobacco mosaic virus by chemical treatment of its nucleic acid in vitro.通过体外化学处理烟草花叶病毒核酸产生突变
Z Vererbungsl. 1958;89(4):614-30.
4
Enhanced mutability associated with a temperature-sensitive mutant of vesicular stomatitis virus.与水疱性口炎病毒温度敏感突变体相关的增强的变异性。
J Virol. 1981 Aug;39(2):377-89. doi: 10.1128/JVI.39.2.377-389.1981.
5
Isolation and preliminary genetic and biochemical characterization of temperature-sensitive mutants of reovirus.呼肠孤病毒温度敏感突变体的分离及初步遗传与生化特性分析
Virology. 1969 Mar;37(3):335-42. doi: 10.1016/0042-6822(69)90217-7.
6
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7
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8
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10
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