Das Pradeep, Roy Seuli Saha, MitraDhar Kakali, Dutta Phalguni, Bhattacharya Mihir K, Sen Abhik, Ganguly Sandipan, Bhattacharya Sujit K, Lal Altaf A, Xiao Lihua
Rajendra Memorial Research Institute of Medical Sciences, Agam Kuan, Patna 800 007, India.
J Clin Microbiol. 2006 Nov;44(11):4246-9. doi: 10.1128/JCM.00091-06. Epub 2006 Sep 13.
The intracellular parasite Cryptosporidium is responsible for severe diarrhea in immunocompromised persons in developing countries. Few studies on the characterization of the parasite in India are available. In this study, molecular characterization of the parasite from diarrheic children was carried out by PCR-restriction fragment length polymorphism analysis. At least three genotypes were identified. Out of 40 positive samples, 35 were positive for C. hominis, 4 were positive for C. parvum, and 1 was positive for C. felis. This study clearly suggests that cryptosporidiosis in this region is caused largely by anthroponotic transmission.
细胞内寄生虫隐孢子虫会导致发展中国家免疫功能低下者出现严重腹泻。在印度，针对该寄生虫特征的研究很少。在本研究中，通过聚合酶链反应-限制性片段长度多态性分析对腹泻儿童体内的寄生虫进行了分子特征分析。至少鉴定出了三种基因型。在40份阳性样本中，35份为人隐孢子虫阳性，4份为微小隐孢子虫阳性，1份为猫隐孢子虫阳性。这项研究清楚地表明，该地区的隐孢子虫病主要是由人传人传播引起的。
