来自印度南部的紫姜富含石竹烯的根茎油：化学表征与抗菌活性。

Caryophyllene-rich rhizome oil of Zingiber nimmonii from South India: Chemical characterization and antimicrobial activity.

作者信息

Sabulal Baby, Dan Mathew, J Anil John, Kurup Rajani, Pradeep Nediyamparambu Sukumaran, Valsamma Renju Krishna, George Varughese

机构信息

Phytochemistry Division, Tropical Botanic Garden and Research Institute, Pacha-Palode, Thiruvananthapuram 695 562, Kerala, India.

出版信息

Phytochemistry. 2006 Nov;67(22):2469-73. doi: 10.1016/j.phytochem.2006.08.003. Epub 2006 Sep 14.

DOI:10.1016/j.phytochem.2006.08.003

PMID:16973189

Abstract

Volatile oil from the rhizomes of Zingiber nimmonii (J. Graham) Dalzell was isolated, characterized by analytical gas chromatography and gas chromatography-mass spectroscopy. Sixty-five constituents accounting for 97.5% of the oil were identified. Z. nimmonii rhizome oil is a unique caryophyllene-rich natural source with isomeric caryophyllenes, beta-caryophyllene (42.2%) and alpha-humulene (alpha-caryophyllene, 27.7%), as its major constituents along with traces of isocaryophyllene. The rhizome oil contained 71.2% sesquiterpenes, 14.2% oxygenated sesquiterpenes, 8.9% monoterpenes, 1.9% oxygenated monoterpenes and 1.3% non-terpenoid constituents. The antimicrobial activity of the oil was tested against human and plant pathogenic bacteria and fungi. The oil showed significant inhibitory activity against the fungi, Candida glabrata, C. albicans and Aspergillus niger and the bacteria Bacillus subtilis and Pseudomonas aeruginosa. No activity was observed against the fungus Fusarium oxysporum.

摘要

从紫姜（Zingiber nimmonii (J. Graham) Dalzell）根茎中分离出挥发油，并通过分析气相色谱和气相色谱-质谱联用对其进行表征。鉴定出占该油97.5%的65种成分。紫姜根茎油是一种独特的富含石竹烯的天然来源，含有异构石竹烯，β-石竹烯（42.2%）和α-葎草烯（α-石竹烯，27.7%）是其主要成分，还含有微量异石竹烯。根茎油中含有71.2%的倍半萜、14.2%的氧化倍半萜、8.9%的单萜、1.9%的氧化单萜和1.3%的非萜类成分。测试了该油对人和植物病原菌及真菌的抗菌活性。该油对光滑念珠菌、白色念珠菌和黑曲霉等真菌以及枯草芽孢杆菌和铜绿假单胞菌等细菌表现出显著的抑制活性。对尖孢镰刀菌未观察到活性。