Memarzadeh Farnaz, Li Yan, Francis Brian A, Smith Ronald E, Gutmark Julie, Huang David
Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine, University of Southern California, 1450 San Pablo Street, DEI5702, Los Angeles, CA 90033, USA.
Br J Ophthalmol. 2007 Feb;91(2):189-92. doi: 10.1136/bjo.2006.100099. Epub 2006 Sep 14.
To evaluate secondary glaucoma after penetrating keratoplasty with anterior-segment optical coherence tomography (OCT).
Case series.
Four eyes of four patients with corneal opacity and increased intraocular pressure (IOP) were evaluated using high-speed (2000 axial scans/s) OCT at 1.3 microm wavelength. Cross-sectional images of the anterior segment were analysed to assess the cause of increase in pressure.
Slit-lamp evaluation of the anterior chamber in all cases was limited by corneal opacity. The OCT imaging allowed visualisation of anterior-segment structures behind the opaque corneas. Using OCT, iris-intraocular lens adhesion and pupillary block were identified as the probable reasons for the increased IOP in one case. Peripheral anterior synechiae and angle closure were identified in the three remaining cases. In two cases, we found that the tip of the aqueous drainage tube was blocked by peripheral anterior synechiae.
OCT is similar to ultrasound in that it allows visualisation through opaque corneas. However, OCT has an advantage in that it requires neither contact nor immersion. It is a valuable tool for evaluating the depth of the anterior chamber angle and the causes of secondary angle closure.
采用眼前节光学相干断层扫描（OCT）评估穿透性角膜移植术后继发性青光眼。
病例系列。
使用波长为1.3微米、速度为2000次轴向扫描/秒的高速OCT对4例角膜混浊且眼压升高的患者的4只眼睛进行评估。分析眼前节的横断面图像以评估眼压升高的原因。
所有病例中前房的裂隙灯检查均受角膜混浊限制。OCT成像可显示混浊角膜后的眼前节结构。通过OCT，在1例病例中确定虹膜-人工晶状体粘连和瞳孔阻滞是眼压升高的可能原因。在其余3例病例中发现周边前粘连和房角关闭。在2例病例中，我们发现房水引流管尖端被周边前粘连阻塞。
OCT与超声类似，能够透过混浊角膜进行成像。然而，OCT的优势在于既不需要接触也不需要浸润。它是评估前房角深度和继发性房角关闭原因的宝贵工具。
