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同一动基体中截然不同的大环类群：是人为现象还是动基体基因组的新特征？

Radically different maxicircle classes within the same kinetoplast: an artefact or a novel feature of the kinetoplast genome?

作者信息

Flegontov Pavel N, Kolesnikov Alexander A

机构信息

Department of Molecular Biology, Lomonosov Moscow State University, Vorobjevy Gory 1, Build. 12, 119992 Moscow, Russia.

出版信息

Kinetoplastid Biol Dis. 2006 Sep 18;5:5. doi: 10.1186/1475-9292-5-5.

DOI:10.1186/1475-9292-5-5
PMID:16978422
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1578572/
Abstract

We discuss here some results which suggest that radically different maxicircle classes coexist within the same kinetoplast. These data, although tentative and incomplete, may provide a new outlook on the kinetoplast genome structure and expression.

摘要

我们在此讨论一些结果，这些结果表明截然不同的大环类在同一动基体中共存。这些数据虽然是初步的且不完整，但可能为动基体基因组的结构和表达提供新的视角。

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本文引用的文献

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Conserved repeats in the kinetoplast maxicircle divergent region of Leishmania sp. and Leptomonas seymouri.利什曼原虫属和西氏细滴虫动质体大环发散区域中的保守重复序列。
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Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and a conserved element in the non-coding region.克氏锥虫线粒体大环显示出物种和菌株特异性变异以及非编码区的一个保守元件。
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The Leishmania major maxicircle divergent region is variable in different isolates and cell types.硕大利什曼原虫的最大环发散区域在不同的分离株和细胞类型中是可变的。
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Variations in maxi-circle and mini-circle sequences in kinetoplast DNAs from different Trypanosoma brucei strains.不同布氏锥虫菌株动质体DNA中最大环和最小环序列的变异
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