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良性前列腺增生的形态计量学评估

Morphometric evaluation of benign prostatic hyperplasia.

作者信息

Siegel Y I, Zaidel L, Hammel I, Korczak D, Lindner A

机构信息

Department of Urology, Edith Wolfson Medical Center, Holon, Israel.

出版信息

Eur Urol. 1990;18(1):71-3. doi: 10.1159/000463872.

DOI:10.1159/000463872
PMID:1698158
Abstract

Resected prostate tissue from 9 patients with benign prostatic hyperplasia was subjected to a morphometric analysis. The relative volume density of 4 prostatic tissue components was determined: fibrous (47%), muscular (8%), vascular (3%), and glandular (18%). The resolution of the stromal portion of the hyperplastic prostate into 3 subcomponents represents a finer level of resolution than that previously reported. This enhanced precision in the determination of tissue composition lends new insight into the etiology of benign prostatic hyperplasia, and provides a basis for the evaluation of novel approaches to its treatment.

摘要

对9例良性前列腺增生患者切除的前列腺组织进行形态计量分析。测定了4种前列腺组织成分的相对体积密度:纤维组织(47%)、肌肉组织(8%)、血管组织(3%)和腺组织(18%)。将增生前列腺的间质部分细分为3个子成分,这比之前报道的分辨率更高。这种在组织成分测定上提高的精确度为良性前列腺增生的病因学提供了新的见解,并为评估其新的治疗方法提供了基础。

相似文献

1
Morphometric evaluation of benign prostatic hyperplasia.良性前列腺增生的形态计量学评估
Eur Urol. 1990;18(1):71-3. doi: 10.1159/000463872.
2
Percentage area density of epithelial and mesenchymal components in benign prostatic hyperplasia: comparison of results between single biopsy, multiple biopsies and multiple tissue specimens.良性前列腺增生中上皮和间充质成分的面积密度百分比:单次活检、多次活检和多个组织标本结果的比较。
Br J Urol. 1995 Mar;75(3):317-24. doi: 10.1111/j.1464-410x.1995.tb07342.x.
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Histopathology of benign prostatic hyperplasia after failure of hyperthermia treatment.热疗治疗失败后良性前列腺增生的组织病理学
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Correlation between morphometric differences and norepinephrine content in benign prostatic hyperplasia.良性前列腺增生症形态学差异与去甲肾上腺素含量之间的相关性
Prostate. 1996 Jun;28(6):385-91. doi: 10.1002/(SICI)1097-0045(199606)28:6<385::AID-PROS8>3.0.CO;2-9.
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Is one single prostate biopsy helpful for choosing a medical treatment of benign prostatic hyperplasia? A quantitative computerized morphometric study.单次前列腺活检对选择良性前列腺增生的医学治疗有帮助吗?一项定量计算机形态测量学研究。
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[Relationship between the quantitative morphometry and the clinical response to alpha adrenergic blocker in benign prostatic hyperplasia].[良性前列腺增生中定量形态学与α-肾上腺素能阻滞剂临床反应的关系]
Nihon Hinyokika Gakkai Zasshi. 1996 Mar;87(3):695-701. doi: 10.5980/jpnjurol1989.87.695.
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Age-related changes of histological composition in established benign prostatic hyperplasia.已确诊良性前列腺增生症组织学构成的年龄相关变化
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Relative and total volume of histological components in benign prostatic hyperplasia: relationships between histological components and clinical findings.良性前列腺增生中组织学成分的相对体积和总体积:组织学成分与临床发现之间的关系。
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Does benign prostatic hyperplasia originate from the peripheral zone of the prostate? A preliminary study.良性前列腺增生是否起源于前列腺外周带?一项初步研究。
BJU Int. 2007 Nov;100(5):1091-6. doi: 10.1111/j.1464-410X.2007.07081.x.

引用本文的文献

1
Effect of the alpha-1 adrenoceptor blocker on tissue norepinephrine contents in human benign prostatic hyperplasia.α-1肾上腺素能受体阻滞剂对人良性前列腺增生组织去甲肾上腺素含量的影响。
Int Urol Nephrol. 1997;29(2):195-200. doi: 10.1007/BF02551341.
2
Norepinephrine contents of human prostatic hyperplasia: differences between pathological subtypes.人前列腺增生组织中去甲肾上腺素含量:病理亚型之间的差异
Int Urol Nephrol. 1996;28(1):61-6. doi: 10.1007/BF02550139.
3
Age-related changes in alpha 1-adrenoceptors in rat prostate.大鼠前列腺中α1肾上腺素能受体的年龄相关变化
Urol Res. 1995;22(6):389-92. doi: 10.1007/BF00296882.