Bartsch G, Frick J, Rüegg I, Bucher M, Holliger O, Oberholzer M, Rohr H P
J Urol. 1979 Oct;122(4):481-6. doi: 10.1016/s0022-5347(17)56475-7.
Normal and benign hyperplastic prostatic tissue was studied by quantitative electron microscopic measurements. Quantitative morphological procedures provide values for volume, surface, number of tissue and cellular components within human prostatic tissue. When a comparison is made of the stereological data of the glandular cell of benign prostatic hyperplasia to that of the normal human prostate no statistically significant difference in the relative volumetric amount of the cell organelles is indicated. An attempt was made to characterize the fine structure of the smooth muscle cells of the stromal area (fibromuscular) in normal and benign hyperplastic prostatic tissue. In benign prostatic hyperplasia a significant increase in the relative amount of organelles in the smooth muscle cell was found, indicating an activation of these cells. Light microscopic analysis has revealed that benign prostatic hyperplasia is primarily a stromal disease.
通过定量电子显微镜测量对正常和良性增生性前列腺组织进行了研究。定量形态学方法可为人体前列腺组织内的体积、表面积、组织和细胞成分数量提供数值。当对良性前列腺增生腺细胞的体视学数据与正常人类前列腺的体视学数据进行比较时，未发现细胞器相对体积量有统计学上的显著差异。有人试图描述正常和良性增生性前列腺组织中基质区域（纤维肌性）平滑肌细胞的精细结构。在良性前列腺增生中，发现平滑肌细胞中细胞器的相对数量显著增加，表明这些细胞被激活。光镜分析显示，良性前列腺增生主要是一种基质疾病。
