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抗菌药物耐药性与患者预后：调整的风险

Antimicrobial resistance and patient outcomes: the hazards of adjustment.

作者信息

Schwaber Mitchell J, Carmeli Yehuda

机构信息

Division of Epidemiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

出版信息

Crit Care. 2006;10(5):164. doi: 10.1186/cc5019.

DOI:10.1186/cc5019
PMID:16982010
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1751076/
Abstract

Outcomes studies of infections with resistant bacteria often do not account appropriately for intermediate variables--events in the causal pathway between the exposure and the outcome--when controlling for confounders. We discuss how failure to distinguish between confounders and intermediate variables can bias the analysis, and we address methods of approaching this issue.

摘要

耐药菌感染的结果研究在控制混杂因素时，往往没有恰当地考虑中间变量，即暴露与结果之间因果路径上的事件。我们讨论了未能区分混杂因素和中间变量如何导致分析产生偏差，并阐述了解决该问题的方法。